Anti-iNOS antibody [EPR16635] (Ab178945)

NOS2A, NOS2, Hepatocyte NOS, Inducible NO synthase, NOS type II, Peptidyl-cysteine S-nitrosylase NOS2, HEP-NOS, Inducible NOS, iNOS

反应种属:Human, Mouse, Rat
抗原名称:NOS2
应用:WB, ELISA, IF/ICC, IP

详细信息

免疫原The exact immunogen used to generate this antibody is proprietary information.
宿主/亚型Rabbit / IgG
抗体类型Monoclonal
产品形式Liquid
纯化方式Affinity purification Protein A
储存缓冲液Preservative: 0.01% Sodium azide Constituents: PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA
储存条件运输条件: Conditional Ambient 推荐的短期储存时间: 1-2 weeks 推荐的短期储存条件: +4°C 推荐的长期储存条件: -20°C 储存信息: Avoid freeze / thaw cycle
无载体蛋白No

特异性

This antibody shows low affinity on human samples. Based on our preliminary data, this antibody is not suitable for THP1 (Human monocytic leukemia monocyte) cell lines in WB.

背景信息

Anti-iNOS antibody [EPR16635] (ab178945) was developed by Abcam using patented rabbit monoclonal antibody technology and is validated for use in I-ELISA, ICC/IF, IP and WB. Anti-iNOS antibody [EPR16635] (ab178945) was first used in a scientific publication in 2014 and has been cited over 275 times in peer reviewed journals. It's performance in Western Blot in human and mouse samples is trusted by the scientific community. Abcam's high quality manufacturing and validation processes ensure Anti-iNOS antibody [EPR16635] (ab178945) has high sensitivity and specificity alongside high lot-to-lot consistency and reproducibility. Anti-iNOS antibody [EPR16635] (ab178945) specifically detects iNOS (UniProt ID: P35228; Molecular weight: 132kDa) and is sold in 100 µL and 1 mL selling sizes. Conjugation-ready, carrier free format available for antibody clone EPR16635 - ab213987. Antibody clone EPR16635 is also available pre-conjugated to a variety of labels for your convenience - Alexa Fluor ® 647, Alexa Fluor ® 555, Alexa Fluor ® 568 ( ab209027, ab209594, ab209595 ). Inducible nitric oxide synthase (iNOS) plays a key role in disease by producing nitric oxide (NO), which can contribute to inflammation and tissue damage in conditions like arthritis, sepsis and cancer. EPR16635 is one of the top cited recombinant antibodies on the market with over 494 citations. Patented technology Our RabMAb ® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb ® patents. What are the advantages of a recombinant monoclonal antibody? This product is a recombinant monoclonal antibody, which offers several advantages including - High batch-to-batch consistency and reproducibility - Improved sensitivity and specificity - Long-term security of supply - Animal-free batch production For more information, read more on recombinant antibodies.

文献引用 (590)

Small extracellular vesicle-integrated by herbal hydrogels for spatiotemporal immunomodulation and neurovascular repair following traumatic brain injury.

小型细胞外囊泡通过草药水凝胶整合,用于创伤性脑损伤后的时空免疫调节和神经血管修复。

Wu Yao, Sun Yuanyuan, Chen Jingjing, Hu Mingrui, Zhang Xindi, Xiong Xinyu, Yu Zhe, Yang Xiya, Li Hui, Wang Yang

MSC-mimicking nanovesicle embedded bio-adhesive hydrogel for dual immunomodulation and osteogenesis to promote maxillofacial bone regeneration.

模拟 MSC 纳米囊泡的生物粘附水凝胶,具有双重免疫调节和成骨作用,可促进颌面骨再生。

Yu Tingting, Yan Jiale, Wang Jingwei, Song Zhiqiang, Bai Rushui, Lu Yuntao, Niu Qin, Cai Tianyu, Han Bing, Wang Xing, Wei Yan

Immune-activating PTL/nanowire composite coating on Ti surface enables macrophage-driven bacterial clearance and osseointegration.

在钛表面涂覆免疫激活PTL/纳米线复合涂层,可实现巨噬细胞驱动的细菌清除和骨整合。

Hang Ruiyue, Chen Huanming, Yang Liwei, Di Ruoyu, Zhao Yuyu, Yao Runhua, Yao Xiaohong, Wang Huaiyu, Xiao Yin, Hang Ruiqiang

On-demand mild photothermal cascade platform reprogramming mitochondrial immunity for tendon rejuvenation.

按需温和光热级联平台重编程线粒体免疫以实现肌腱再生。

Zheng Zitian, Hu Yichen, Zhu Yucheng, Zhang Hanchen, Yang Meng, Ding Guocheng, Wu Yang, Yang Fan, Lu Boyun, Zhou Zheng, Liu Xiaojun, Zhang Guanxin, Zhang Xin, Zhang Deqing, Wang Jianquan, Huang Hongjie

A DNA Tetrahedron Delivery Asiatic Acid to Reprogram Mitochondrial Metabolism for Promoting Bone Regeneration via STAT3 Phosphorylation.

通过 STAT3 磷酸化重编程线粒体代谢以促进骨骼再生的 DNA 四面体递送积雪草酸。

Huang Yiwen, Zhang Yiming, Feng Yisheng, Yang Qixiang, Gao Beiyuan, Xu Haiyang, Huang Cheng, Lin Kaili, Xu Yuanzhi, Zhu Peiqi

α-Ketoglutarate protects against cartilage damage via epigenetically driven metabolic reprogramming in osteoarthritis models.

α-酮戊二酸通过表观遗传驱动的代谢重编程在骨关节炎模型中保护软骨免受损伤。

Microglial TIA1-mediated stress granules promote neuroinflammation and aggravate neuron loss in mice after ischemic stroke by inhibiting IGF2 signaling.

小胶质细胞 TIA1 介导的应激颗粒通过抑制 IGF2 信号传导,促进缺血性中风后小鼠的神经炎症并加剧神经元丢失。

Qian Yiming, Yu Hong, Dong Jianhong, Liu Jinyuan, Han Jiaqi, Zheng Tianwen, Zhang Wei, Wang Lipei, Huang Zhihui, Wang Ying

Pathology-tailored nanotherapy via Galectin-3-targeted and triple-responsive nanoparticles enables multimodal therapy against aortic dissection.

通过针对 Galectin-3 的三重响应纳米颗粒进行病理定制的纳米疗法,可以实现针对主动脉夹层的多模式治疗。

Lin Chi, Tsai Min-Lang, Chao Hsin-Yi, Cheng Tsai-Mu, Shih Chun-Ming, Wu Alexander T H, Cheng Chia-Hsiung, Hsiao Chen Yuan, Lu Hsin-Ying, Shih Chun-Che, Mi Fwu-Long

Poly-l-lactic acid electrospun membrane with specific morphology promotes bone regeneration through macrophage reprogramming.

具有特定形态的聚左旋乳酸电纺膜通过巨噬细胞重编程促进骨再生。

Tang Daiyuan, Xu Yunrong, Huang Zaitian, Xiao Zhenping, Sun Chenxun, Li Jingyu, He Fei, Han Bing, Zhu Chen

Spatiotemporal Co-Delivery of Hydrogen and Magnesium via Microneedle Patches for Neuroinflammation Modulation After Spinal Cord Injury: A Multi-Modal In Vivo Study.

通过微针贴片进行氢和镁的时空共递送以调节脊髓损伤后的神经炎症:一项多模式体内研究。

Wang Haibo, Sun Yang, Wang Shiqi, Wang Wenbo, Tang Jincheng, Li Ziang, Jiang Xinzhao, Zhou Liang, Wu Jie, Guo Qiangqiang, Zhu Yiwei, Feng Yu, Xi Kun, Chen Liang
  • 1
  • 2
  • 3
  • 4
  • 5
  • 6
  • 59