Anti-HMGB1 antibody (Ab18256)

HMG1, HMGB1, High mobility group protein B1, High mobility group protein 1, HMG-1

反应种属:Human, Mouse, Rat
抗原名称:HMGB1
应用:WB, IF/ICC

详细信息

免疫原The exact immunogen used to generate this antibody is proprietary information.
宿主/亚型Rabbit / IgG
抗体类型Polyclonal
产品形式Liquid
纯化方式Affinity purification Immunogen
储存缓冲液pH: 7.4 Preservative: 0.02% Sodium azide Constituents: PBS, 1% BSA
储存条件运输条件: Blue Ice 推荐的短期储存时间: 1-2 weeks 推荐的短期储存条件: +4°C 推荐的长期储存条件: -20°C 储存信息: Avoid freeze / thaw cycle

背景信息

Product Specifications Anti-HMGB1 antibody (ab18256) is a rabbit polyclonal antibody and is validated for use in ICC/IF, WB in human, mouse, rat samples. Anti-HMGB1 antibody (ab18256) specifically detects HMGB1 (UniProt ID: P09429; Molecular weight: 25kDa) and is sold in 100 µg selling sizes. Quality and Validation Abcam's high quality validation processes ensure Anti-HMGB1 antibody (ab18256) has high sensitivity and specificity. The specificity of Anti-HMGB1 antibody (ab18256) has been confirmed by testing in knockout samples. Anti-HMGB1 antibody (ab18256) has been cited over 577 times in peer reviewed journals and is trusted by the scientific community. Anti-HMGB1 antibody (ab18256) has 92 independent reviews from customers.

文献引用 (647)

Boron neutron capture therapy preserves immune cells and induces robust anti-tumour immunity in preclinical mouse model.

硼中子俘获疗法可在临床前小鼠模型中保护免疫细胞并诱导强大的抗肿瘤免疫力。

Sun Qi, Zhao Yanping, Qiao Simiao, Wang Kexuan, Lu Chuanjie, Zhang Zizhu, Guo Zhibin, Ding Zexuan, Wang Chunhong, Li Jiyuan, Liu Tong, Zeng Zexian, Liu Zhibo

Caspase-3/GSDME-Mediated Trophoblast Pyroptosis and Reciprocal Macrophage Polarization Contribute to Inflammation in Early-Onset Preeclampsia.

Caspase-3/GSDME介导的滋养层细胞焦亡和相互巨噬细胞极化促进早发型子痫前期的炎症反应。

Huang Baoying, Deng Weinan, Bi Shilei, Wang Yifan, Tu Zhaowei, Huang Lijun, Du Lili, Zhang Lizi, Feng Zhoushan, Sun Wei, Liu Tengfei, Kzhyshkowska Julia, Wang Haibin, Chen Jingsi, Chen Dunjin, Zhang Shuang

Biomineralized OMV-based nanocomposite orchestrates cascade-amplified antitumor immunity via eliciting dual pyroptosis and blocking autophagy.

基于生物矿化 OMV 的纳米复合材料通过诱导双重细胞焦亡和阻断自噬来协调级联放大的抗肿瘤免疫。

Wang Yi, Luo Ying, Zhang Wenli, Liu Jia, Liu Yun, Zhang Yu, Xu Jie, Xu Zhongsheng, Liu Bo, Chen Sijin, Rong Xiyue, Xu Lian, Du Qianying, Ran Haitao, Wang Zhigang, Guo Dajing

Innate immune sensing of dietary alcohol ignites inflammation to drive alcohol-related disease.

人体免疫系统对膳食酒精的感知会引发炎症,从而导致酒精相关疾病。

Jang Yeonseo, Bae Hoeun, Oh SuHyeon, Yu Gyeongju, Bae Hyun, Nguyen Minh Quan, Mall Raghvendra, Fu Minjie, Ghosh Aritra, Lee Jihye, Kim Suhyun, Shin Seyun, Mariam Nabukenya, Seok Cheong, Kim Daesik, Lee SangJoon, Man Si Ming, Karki Rajendra

A photodynamically activated nanoplatform relieves glucose-driven immunosuppression to potentiate STING immunotherapy in triple-negative breast cancer.

光动力激活纳米平台可缓解葡萄糖驱动的免疫抑制,从而增强 STING 免疫疗法在三阴性乳腺癌中的疗效。

Long Yongxuan, Li Jinlin, Chang Menghan, Zhu Huihui, Yang Xu, Lv Yinhua, Sun Yi, Yu Yongqiang, Zhang Weijie

BTLA-mediated regulation of neuroimmune responses enhances recovery after intracerebral hemorrhage.

BTLA介导的神经免疫反应调节可增强脑出血后的恢复。

Wu Yuxing, Zhang Yanping, Fu Peiji, Huang Maosen, Chen Shuai, Li Yi, Wu Tao, Rastegar-Kashkooli Yousef, Cheng Nannan, Zhao Taiqi, Wang Yunlong, Wang Xiaojun, Wang Jian, Wang Junmin, Jiang Chao

Salmonella typhimurium co-expressing cytolysin A and hyaluronidase suppresses tumor growth and metastasis.

沙门氏菌同时表达溶细胞素 A 和透明质酸酶可抑制肿瘤生长和转移。

Nguyen Khuynh Van, Nguyen Dinh-Huy, Ngo Hien Thi-Thu, You Sung-Hwan, Kim So-Young, Hong Yeongjin, Min Jung-Joon

The mechanisms by which hypothalamic neuroinflammation induced by neonatal cerebral ischemia-hypoxia leads to decreased thymic function via the HPA axis.

新生儿脑缺血缺氧引起的下丘脑神经炎症通过HPA轴导致胸腺功能下降的机制。

Liu Gai-Gai, Shuang Li-Yan, Zhang Qian, Su Guang-Jun, Huang Yun, Xue Jin-Hua, Jiang Li-Xia, Huang Cheng, Chen Tao, Huang Zhi-Hua, Cao Si

Dysregulated hyaluronan metabolism drives inflammation and angiogenesis in proliferative diabetic retinopathy.

透明质酸代谢失调驱动增殖性糖尿病视网膜病变中的炎症和血管生成。

Abu El-Asrar Ahmed M, Nawaz Mohd I, Ahmad Ajmal, Siddiquei Mairaj, Allegaert Eef, Gikandi Priscilla W, De Hertogh Gert, Opdenakker Ghislain

Albumin-bound paclitaxel drives a cytotoxic CD8(+) T cell enriched immune microenvironment in triple negative breast cancer.

白蛋白结合的紫杉醇可促进三阴性乳腺癌中富含细胞毒性 CD8(+) T 细胞的免疫微环境。

Luo Daiqin, Jin Xianhuai, Zhang Shuai, Zeng Xianlin, Zhang Shuling, Li Daohong, Xiong Wei, Luo Yan, Hu Zuquan, Long Jinhua, Zeng Zhu
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