Anti-PSD95 antibody - Synaptic Marker (Ab18258)
PSD95, DLG4, Disks large homolog 4, Postsynaptic density protein 95, Synapse-associated protein 90, PSD-95, SAP-90, SAP90
详细信息
背景信息
Anti-PSD95 antibody - Synaptic Marker (ab18258) is a rabbit polyclonal antibody and is validated for use in ICC/IF, IHC-P and WB. Anti-PSD95 antibody - Synaptic Marker (ab18258) was first used in a scientific publication in 2001 and has been cited over 366 times in peer reviewed journals. It's performance in Western blot and IHC in human, mouse and rat samples is trusted by the scientific community. Abcam's high quality validation processes ensure Anti-PSD95 antibody - Synaptic Marker (ab18258) has high sensitivity and specificity. The specificity of Anti-PSD95 antibody - Synaptic Marker (ab18258) has been confirmed by WB testing in PSD95 knockout SH-SY5Y cells ( ab280043 ). Anti-PSD95 antibody - Synaptic Marker (ab18258) has 39 independent reviews from customers. Anti-PSD95 antibody - Synaptic Marker (ab18258) specifically detects PSD95 (UniProt ID: P78352; Molecular weight: 81kDa) and is sold in 100 ug selling sizes. PSD95 (Postsynaptic Density Protein 95), encoded by gene DLG4, is a crucial scaffolding protein in neuro research, particularly for its role in synaptic stability and plasticity. It is involved in the organization of synaptic signaling complexes and the regulation of synaptic strength. Researchers use PSD95 to study synaptic development, neurotransmitter receptor localization and the effects of neurological disorders such as stroke and traumatic brain injury (TBI). Its expression helps in understanding synaptic function and the molecular mechanisms underlying synaptic plasticity and neuroprotection.
文献引用 (458)
Single-cell spatiotemporal transcriptomic and chromatin accessibility profiling in developing postnatal human and macaque prefrontal cortex.
人类和猕猴出生后前额叶皮层发育过程中的单细胞时空转录组和染色质可及性分析。
Remodeling synaptic connections via engineered neuron-astrocyte interactions.
通过工程化神经元-星形胶质细胞相互作用重塑突触连接。
Metabolites released from apoptotic cells in central nervous system orchestrates the pathological process of Alzheimer disease through improving autophagy.
中枢神经系统凋亡细胞释放的代谢物通过改善自噬作用来调控阿尔茨海默病的病理过程。
Single-Nucleus RNA Sequencing Reveals Mid-Gestational Neurodevelopment Features in the Superior Temporal Plane from Fetuses with Nonsyndromic Cleft Lip and Palate.
单核 RNA 测序揭示非综合征性唇腭裂胎儿上颞平面中期妊娠神经发育特征。
Distinct neuronal alterations distinguish two subtypes of sporadic Creutzfeldt-Jakob disease with shared dysfunctional pathways.
散发性克雅氏病的两个亚型具有不同的神经元改变，但它们都存在共同的功能障碍通路。
Pharmacologic reversal of advanced Alzheimer's disease in mice and identification of potential therapeutic nodes in human brain.
药物逆转小鼠晚期阿尔茨海默病并识别人类大脑中潜在的治疗节点。
Downregulation of neuronal DRD2 drives microglia synaptic pruning and results in cognitive deficits by promoting CCL2 release in a rat model of chronic migraine
在慢性偏头痛大鼠模型中，神经元DRD2的下调驱动小胶质细胞突触修剪，并通过促进CCL2释放导致认知缺陷。
Adipose-Specific GHR Deletion Attenuates Brain Aging and Cognitive Decline in Aged Mice.
脂肪组织特异性 GHR 缺失可减轻老年小鼠的大脑衰老和认知能力下降。
CSF1R T567M mutation induces microglial dysfunction and synaptic impairment in patient iPSC-derived cerebral organoids of CSF1R-related disorder.
CSF1R T567M 突变导致 CSF1R 相关疾病患者的 iPSC 衍生脑类器官中小胶质细胞功能障碍和突触损伤。
Ascorbic acid enhances antidepressant-like efficacy of esketamine: Hippocampal TARP-γ8-containing AMPA receptors mediate synaptic modulation.
抗坏血酸增强艾司氯胺酮的抗抑郁样功效：海马 TARP-γ8 含 AMPA 受体介导突触调节。
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