Anti-Oct4 antibody [EPR17929] - ChIP Grade (Ab181557)
OCT3, OCT4, OTF3, POU5F1, Octamer-binding protein 3, Octamer-binding protein 4, Octamer-binding transcription factor 3, Oct-3, Oct-4, OTF-3
详细信息
特异性
Oct4 is highly expressed in undifferentiated embryonic stem cells and cancer stem cell-like cells (PMID: 26013162, 21826175). This antibody can't detect the target band in undifferentiated cancer cell lines with low expression level of Oct4, such as HeLa, HEK-293, MDA-MB-231, HepG2, Huh7, HCT-116 and PANC-1 (PMID: 21975933, 29789579, 25625591, 26059097, 23928699, 27344963, 25837691, 29254202, 28854261, 27996162), even at the dilution of 1:200.
背景信息
Product Specifications Anti-Oct4 antibody [EPR17929] - ChIP Grade (ab181557) was developed by Abcam using patented rabbit monoclonal antibody technology and is validated for use in ChIP, ChIP-seq, Flow Cyt (Intra), ICC/IF, IHC-P, IP, WB in human, mouse samples. Anti-Oct4 antibody [EPR17929] - ChIP Grade (ab181557) specifically detects Oct4 (UniProt ID: Q01860; Molecular weight: 39kDa) and is sold in 100 µL and 1 mL selling sizes. Quality and Validation Abcam's high quality manufacturing and validation processes ensure Anti-Oct4 antibody [EPR17929] - ChIP Grade (ab181557) has high sensitivity and specificity alongside high lot-to-lot consistency and reproducibility. Anti-Oct4 antibody [EPR17929] - ChIP Grade (ab181557) has been cited over 138 times in peer reviewed journals and is trusted by the scientific community. Anti-Oct4 antibody [EPR17929] - ChIP Grade (ab181557) has 19 independent reviews from customers. Related Products Antibody clone EPR17929 is also available pre-conjugated to a variety of labels for your convenience - Alexa Fluor® 594, Alexa Fluor® 555, PE, Alexa Fluor® 488, Alexa Fluor® 647 ( ab210458, ab210657, ab283731, ab283741, ab300092 ). Patented technology Our RabMAb ® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb ® patents. What are the advantages of a recombinant monoclonal antibody? This product is a recombinant monoclonal antibody, which offers several advantages including - High batch-to-batch consistency and reproducibility - Improved sensitivity and specificity - Long-term security of supply - Animal-free batch production For more information, read more on recombinant antibodies.
文献引用 (190)
Poking Pluripotency: Nanoinjection Into Human iPSCs.
激发多能性:纳米注射到人类诱导多能干细胞中。
Essential role of NONO-HOXA1-Wnt axis in cardiomyocyte differentiation.
NONO-HOXA1-Wnt轴在心肌细胞分化中起着至关重要的作用。
Mosaic partial epidermal reprogramming remodels neighbors and niches to refine skin homeostasis and repair.
表皮部分重塑嵌合体重塑邻近细胞和微环境,以改善皮肤稳态和修复。
Autophagy dictates PHGDH-mediated serine metabolism in a timely manner to support oocyte development.
自噬及时调控PHGDH介导的丝氨酸代谢,以支持卵母细胞发育。
Depletion of Sorcs3 Activates Totipotency in Mouse Embryonic Stem Cells by Modulating Key Signaling Pathways.
Sorcs3 的缺失通过调节关键信号通路激活小鼠胚胎干细胞的全能性。
H3K9me2 is a determinant for the mitosis-to-meiosis transition in female germ cells.
H3K9me2 是雌性生殖细胞有丝分裂向减数分裂转变的决定因素。
Inflammation-induced LncRNA SNHG1 orchestrates spermatogonium development in non-obstructive azoospermia via IL-17Â A signaling pathway.
炎症诱导的 LncRNA SNHG1 通过 IL-17A 信号通路调控非梗阻性无精子症中的精原细胞发育。
APOE4 drives widespread changes to the hepatic proteome and alters metabolic function.
APOE4 驱动肝脏蛋白质组发生广泛变化,并改变代谢功能。
The lysosomal cysteine protease cathepsin L promotes stemness and multidrug resistance of non-small cell lung cancer by targeting HGF activator.
溶酶体半胱氨酸蛋白酶组织蛋白酶 L 通过靶向 HGF 激活剂促进非小细胞肺癌的干性和多药耐药性。
Profiling and functional analysis of exosomal circRNAs from EBV-associated gastric carcinoma CSCs.
EBV相关胃癌干细胞外泌体环状RNA的谱分析和功能分析。
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