Anti-F4/80 antibody [EPR26545-166] (Ab300421)

Emr1, Gpf480, Adgre1, Adhesion G protein-coupled receptor E1, Cell surface glycoprotein F4/80, EGF-like module receptor 1, EGF-like module-containing mucin-like hormone receptor-like 1, EMR1 hormone receptor

反应种属:Mouse, Rat
抗原名称:Adgre1
应用:WB, IHC, IF/ICC, MIHC

用户验证的应用

推荐稀释比例

  • IHC-P1/5000 Perform heat-mediated antigen retrieval with Tris/EDTA buffer pH 9.0 before commencing with IHC staining protocol.
  • mIHC1/5000 Perform heat-mediated antigen retrieval with Tris/EDTA buffer pH 9.0 before commencing with IHC staining protocol.
  • WB1/1000 Not suitable for Rat.
  • ICC/IF1/50
  • IHC-Fr1/500

详细信息

免疫原The exact immunogen used to generate this antibody is proprietary information.
宿主/亚型Rabbit / IgG
抗体类型Monoclonal
全称Anti-F4/80 antibody [EPR26545-166]
产品形式Liquid
储存缓冲液pH: 7.2 - 7.4 Preservative: 0.01% Sodium azide Constituents: PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA
储存条件运输条件: Conditional Ambient 推荐的短期储存时间: 1-2 weeks 推荐的短期储存条件: +4°C 推荐的长期储存条件: -20°C 储存信息: Avoid freeze / thaw cycle
纯化方式Affinity purification Protein A

背景信息

Anti-F4/80 antibody [EPR26545-166] (ab300421) was developed by Abcam using patented rabbit monoclonal antibody technology and is validated for use in ICC/IF, IHC-Fr IHC-P, WB and mIHC. Abcam's high quality manufacturing and validation processes ensure Anti-F4/80 antibody [EPR26545-166] (ab300421) has high sensitivity and specificity alongside high lot-to-lot consistency and reproducibility. Anti-F4/80 antibody [EPR26545-166] (ab300421) specifically detects F4/80 (UniProt ID: Q61549; Molecular weight: 99kDa) and is sold in a convenient trial size to enable initial testing (20 µL) and larger sizes for subsequent scaling up experiments (100 µL and 1 mL). Conjugation-ready, carrier free format available for antibody clone EPR26545-166 - ab300422. Antibody clone EPR26545-166 is also available pre-conjugated to a variety of labels for your convenience - Alexa Fluor ® 647 ( ab307470 ). F4/80 is a key marker for macrophages, playing a significant role in immune response modulation and inflammation and is linked to various inflammatory diseases. Patented technology Our RabMAb ® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb ® patents. What are the advantages of a recombinant monoclonal antibody? This product is a recombinant monoclonal antibody, which offers several advantages including - High batch-to-batch consistency and reproducibility - Improved sensitivity and specificity - Long-term security of supply - Animal-free batch production For more information, read more on recombinant antibodies.

文献引用 (146)

The Regulatory Role of Iron Transporter SLC39A13 in Liver Fibrosis.

铁转运蛋白SLC39A13在肝纤维化中的调控作用。

Guo Shanshan, Wang Yalin, Lu Binyu, Zhang Yu, Frazer David M, Zhou Bing

The GOLM1-ACLY pathway regulates macrophage-secreted EFEMP1 via H3K27ac modifications to drive tumor progression.

GOLM1-ACLY 通路通过 H3K27ac 修饰调节巨噬细胞分泌的 EFEMP1,从而驱动肿瘤进展。

A novel Kupffer cell-targeting nanoparticle system to Mitigate alcohol-associated liver disease.

一种新型的库普弗细胞靶向纳米颗粒系统,用于缓解酒精相关性肝病。

Unagolla Janitha M, Flanagan Riley, Perera Kalindu, Kim Youbin, Soloff Curtis, Kaye Emily, Slitt Angela, Menon Jyothi U

CEBPB-high dormant tumor cells drive immune evasion via S100A8 orchestrated tumor-associated macrophages reprogramming

CEBPB高表达的休眠肿瘤细胞通过S100A8调控的肿瘤相关巨噬细胞重编程驱动免疫逃逸

Jin Bai,Huilan Su,Shunxi Wang,Yang Dong,Yong Gao

Mannose Oligosaccharide-Conjugated In Situ Pore-Forming Injectable Hydrogels for Rheumatoid Arthritis Treatment by Reprogramming Macrophage Extracellular Vesicles

通过重编程巨噬细胞外囊泡,制备用于治疗类风湿性关节炎的甘露糖寡糖偶联原位成孔注射水凝胶

Anan Zhang,Yifan Ma,Yutong Liu,Shiyan Dong,Michelle Najarro Torres,Betty Y S Kim,Changsheng Liu,Lili Sun,Yuan Yuan,Wen Jiang

Tet2 deficiency-induced expansion of monocyte-derived macrophages promotes liver fibrosis.

Tet2 缺乏诱导的单核细胞衍生巨噬细胞扩增促进肝纤维化。

Feng Jiuxing, Wu Baitong, Li Yu, Sun Pengli, Liu Qian, Xiao Qianxue, Cai Jia-Bin, Zheng Yimin, Chen Haonan, Xu Yichi, Liu Yixin, Shi Guo-Ming, Tan Li, Shi Yujiang Geno

Dual PD-1/IL-2Rα targeting restores CD8(+) T cell fitness via STAT5/CD47 axis in SMARCA4-deficient NSCLC.

双重 PD-1/IL-2Rα 靶向治疗通过 STAT5/CD47 轴恢复 SMARCA4 缺陷型 NSCLC 中的 CD8(+) T 细胞功能。

Synthetic cleavage-resistant TREM2 boosts macrophage efferocytosis to treat inflammatory diseases.

合成的抗裂解TREM2可增强巨噬细胞吞噬作用,用于治疗炎症性疾病。

Hierarchical Porous Egg White Hydrogel Promotes Diabetic Wound Closure through Topography-Guided Cell Recruitment.

分级多孔蛋清水凝胶通过地形引导的细胞募集促进糖尿病伤口愈合。

Su Ting, Niu Xingtang, Wang Xinhui, Sun Dan, Xu Mimi, He Yu, Huang Xiaoqi, Ma Yuan, Chang Qiang, Lu Feng

Escherichia coli Nissle 1917 Modulates the RNF150/ELAVL1 Ubiquitination Pathway to Ameliorate Obesity-driven Insulin Resistance in High-fat Diet-fed Mice.

大肠杆菌 Nissle 1917 调节 RNF150/ELAVL1 泛素化途径,以改善高脂饮食喂养小鼠的肥胖驱动的胰岛素抵抗。

  • 1
  • 2
  • 3
  • 4
  • 5
  • 6
  • 15