Anti-Ctip2 antibody [25B6] (Ab18465)

特异性

Detects 2 bands representing Ctip2 at about 120kD. Ctip2 is highly expressed in brain and in malignant T-cell lines derived from patients with adult T-cell leukemia/lymphoma. While we do not guarantee suitability of ab18465 for IHC-Fr, some customers have reported successful use in this application. See PMID: 24739528 for example.

Anti-Ctip2 antibody [25B6] (ab18465) is a rat monoclonal antibody and is validated for use in Flow Cyt (Intra), ICC/IF, IHC-P and WB. Anti-Ctip2 antibody [25B6] (ab18465) was first used in a scientific publication in 2001 and has been cited over 841 times in peer reviewed journals. It's performance in immunofluorescence and IHC in human and mouse samples is trusted by the scientific community. Abcam's high quality validation processes ensure Anti-Ctip2 antibody [25B6] (ab18465) has high sensitivity and specificity. Anti-Ctip2 antibody [25B6] (ab18465) has 35 independent reviews from customers. Anti-Ctip2 antibody [25B6] (ab18465) specifically detects Ctip2 (UniProt ID: Q9C0K0; Molecular weight: 96kDa) and is sold in 100 µg selling sizes. Antibody clone 25B6 is also available pre-conjugated to a variety of labels for your convenience - FITC ( ab123449 ). CTIP2, also known as BCL11B, is a transcription factor crucial in neuro research for its role in neural development and differentiation. It is particularly important for the development of medium spiny neurons (MSNs) in the striatum, which are essential for motor control and are affected in conditions like Huntington's disease. CTIP2 regulates gene expression involved in neuronal differentiation, axon guidance and synaptic connectivity, making it vital for understanding the cellular architecture and function of the nervous system.