Anti-Doublecortin antibody (Ab18723)
DBCN, LISX, DCX, Neuronal migration protein doublecortin, Doublin, Lissencephalin-X, Lis-X
详细信息
特异性
Please note: Low dilutions of this antibody can cause high background in IHC. Please use as high a dilution as possible. Optimal working dilutions are batch dependent.
背景信息
Anti-Doublecortin antibody (ab18723) is a rabbit polyclonal antibody and is validated for use in ICC/IF, IHC-FoFr, IHC-Fr, IHC-P and WB. Anti-Doublecortin antibody (ab18723) was first used in a scientific publication in 2004 and has been cited over 474 times in peer reviewed journals. It's performance in Western blot and IHC in human, mouse and rat samples is trusted by the scientific community. Abcam's high quality validation processes ensure Anti-Doublecortin antibody (ab18723) has high sensitivity and specificity. Anti-Doublecortin antibody (ab18723) has 59 independent reviews from customers. Anti-Doublecortin antibody (ab18723) specifically detects Doublecortin (UniProt ID: O43602; Molecular weight: 41kDa) and is sold in 50 µg selling sizes. Doublecortin (DCX) is a critical protein in neuro research, particularly for its role in neuronal migration and neurogenesis. It is predominantly expressed in immature neurons and is essential for proper brain development. Researchers use doublecortin to study the formation and migration of new neurons, making it vital for understanding neurodevelopmental disorders and brain repair mechanisms. Its expression helps in assessing the dynamics of neuronal growth and the potential for neuroplasticity in various neurological conditions.
文献引用 (529)
Piezo1 induces Wnt7b+ astrocytes transformation to modulate glial scar stiffness and neuro-regeneration after stroke
Piezo1诱导Wnt7b+星形胶质细胞转化,从而调节卒中后胶质瘢痕的硬度和神经再生。
Age-mimicking hydrogel stiffness recapitulates the mechanical niche of the hippocampus to regulate neural stem cell senescence.
模拟衰老的水凝胶刚度重现了海马体的机械环境,从而调节神经干细胞衰老。
Colitis-associated gut-vagus-brain signaling integrates tumorigenesis and neuroinflammation: comparative regulation by vagotomy and atropine.
结肠炎相关的肠-迷走神经-脑信号整合肿瘤发生和神经炎症:迷走神经切断术和阿托品的比较调节。
MYRF controls mesothelium specification, signaling, and plasticity in lung development.
MYRF 控制肺发育过程中间皮细胞的分化、信号传导和可塑性。
Alleviation of mutant TDP-43-mediated neuropathology by inducible stem cells in monkeys
利用诱导干细胞缓解猴子体内突变型TDP-43介导的神经病理学
DKK2 contributes to context discrimination and adult hippocampal neurogenesis by suppressing Wnt/PCP signaling.
DKK2 通过抑制 Wnt/PCP 信号传导,促进情境辨别和成年海马神经发生。
Active Components of Ginkgo biloba Flower Attenuate Radiation-Induced Cognitive Impairment via Inhibiting Ferroptosis.
银杏花活性成分通过抑制铁死亡减轻辐射引起的认知障碍。
Tropism-shifted AAV-PHP.eB-mediated bFGF gene therapy promotes varied neurorestoration after ischemic stroke in mice
嗜性转变的AAV-PHP.eB介导的bFGF基因疗法可促进小鼠缺血性卒中后的多种神经修复
N-Stearidonoylethanolamine Restores CA1 Synaptic Integrity and Reduces Astrocytic Reactivity After Mild Traumatic Brain Injury.
N-硬脂酰乙醇胺可恢复 CA1 突触完整性并降低轻度创伤性脑损伤后的星形胶质细胞反应性。
Sodium pyruvate ameliorates cognitive dysfunction by expanding hippocampal endogenous neural stem cells in tBCCAO mice.
丙酮酸钠通过扩增 tBCCAO 小鼠海马内源性神经干细胞来改善认知功能障碍。
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