Anti-Bcl-2 antibody [EPR17509] (Ab182858)
Apoptosis regulator Bcl-2, BCL2
用户验证的应用
推荐稀释比例
- IHC-P1/500 Perform heat-mediated antigen retrieval with Tris/EDTA buffer pH 9.0 before commencing with IHC staining protocol.
- WB1/2000
- Flow Cyt (Intra)1/250
详细信息
背景信息
Anti-Bcl-2 antibody [EPR17509] (ab182858) was developed by Abcam using patented rabbit monoclonal antibody technology and is validated for use in Flow Cyt (Intra), IHC-P and WB. Anti-Bcl-2 antibody [EPR17509] (ab182858) was first used in a scientific publication in 2016 and has been cited over 632 times in peer reviewed journals. It's performance in Western Blot in human and mouse samples is trusted by the scientific community. Abcam's high quality manufacturing and validation processes ensure Anti-Bcl-2 antibody [EPR17509] (ab182858) has high sensitivity and specificity alongside high lot-to-lot consistency and reproducibility. The specificity of Anti-Bcl-2 antibody [EPR17509] (ab182858) has been confirmed by Western Blot testing in Bcl-2 knockout HeLa cells ( ab263752 ). Anti-Bcl-2 antibody [EPR17509] (ab182858) has 13 independent reviews from customers. Anti-Bcl-2 antibody [EPR17509] (ab182858) specifically detects Bcl-2 (UniProt ID: P10415; Molecular weight: 27kDa) and is sold in 100 µL and 1 mL selling sizes. Conjugation-ready, carrier free format available for antibody clone EPR17509 - ab219608. Antibody clone EPR17509 is also available pre-conjugated to a variety of labels for your convenience - HRP ( ab209039 ). B-cell lymphoma 2 (Bcl-2) is a key protein in oncology, known for its role in regulating apoptosis, or programmed cell death. It promotes cell survival by inhibiting pro-apoptotic proteins, thereby preventing apoptosis and contributing to the development and progression of various cancers. Patented technology Our RabMAb ® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb ® patents. What are the advantages of a recombinant monoclonal antibody? This product is a recombinant monoclonal antibody, which offers several advantages including - High batch-to-batch consistency and reproducibility - Improved sensitivity and specificity - Long-term security of supply - Animal-free batch production For more information, read more on recombinant antibodies.
文献引用 (1102)
Mitochondrial protein-enriched artificial nanovesicles: mitochondrial recovery and antioxidation for diabetic wound treatment.
富含线粒体蛋白的人工纳米囊泡:用于糖尿病伤口治疗的线粒体恢复和抗氧化作用。
Iron single-atom nanozyme-mediated laser interstitial thermal therapy and anti-inflammatory effect for epilepsy.
铁单原子纳米酶介导的激光间质热疗及抗炎作用治疗癫痫。
Complement protein C1q induces endothelial apoptosis through C1qBP regulation of mitochondrial function in lung endothelial cells in systemic sclerosis.
补体蛋白 C1q 通过 C1qBP 调节肺内皮细胞的线粒体功能,诱导系统性硬化症中的内皮细胞凋亡。
FBXO39 knockdown promotes spermatogenesis impairment by inducing mitochondrial dysfunction and ferroptosis via inhibiting KDM5A ubiquitination and regulating H3K4me3 demethylation.
FBXO39 敲低通过抑制 KDM5A 泛素化和调节 H3K4me3 去甲基化,诱导线粒体功能障碍和铁死亡,从而促进精子发生受损。
Impaired Mitophagy-Induced Apoptosis of Gingival Fibroblasts Exacerbates Diabetic Periodontitis Via THBS-1/CD36-Dependent Macrophage Activation.
牙龈成纤维细胞线粒体自噬受损诱导的细胞凋亡通过 THBS-1/CD36 依赖性巨噬细胞活化加剧糖尿病性牙周炎。
Angiotensin II Receptor-Associated Protein (AGTRAP) Enhances Glioma Cell Survival Through the IL-6/JAK2/STAT3 Pathway and Correlates With an Immunosuppressive Microenvironment.
血管紧张素 II 受体相关蛋白 (AGTRAP) 通过 IL-6/JAK2/STAT3 通路增强胶质瘤细胞的存活,并与免疫抑制微环境相关。
IncRNAs transcriptomics elucidates the potential mechanism of Naoshuantong capsule in alleviating synaptic dysfunction in a murine model of cerebral ischemia/reperfusion injury.
IncRNA 转录组学阐明了脑栓通胶囊缓解小鼠脑缺血/再灌注损伤模型中突触功能障碍的潜在机制。
Hsa_circ_0101645 contributes to excessive autophagy and apoptosis in intervertebral disc degeneration by acting as a miR-1304-5p sponge modulating BNIP3 expression.
Hsa_circ_0101645 通过作为 miR-1304-5p 海绵调节 BNIP3 表达,促进椎间盘退变中的过度自噬和细胞凋亡。
CircEif3c/miR-96-5p/PHF20L1/MEOX2 axis in perivascular preadipocyte exosomes mediates fibroblast dysfunction and vascular remodeling.
血管周围前脂肪细胞外泌体中的 CircEif3c/miR-96-5p/PHF20L1/MEOX2 轴介导成纤维细胞功能障碍和血管重塑。
Daixie recipe ameliorates diet-induced MASH in mice via activating PI3K/AKT and Keap1/Nrf2 signaling.
Daixie 配方通过激活 PI3K/AKT 和 Keap1/Nrf2 信号通路来改善饮食引起的小鼠 MASH 症状。
- 1
- 2
- 3
- 4
- 5
- 6
- 111