Anti-Oct4 antibody (Ab19857)

OCT3, OCT4, OTF3, POU5F1, Octamer-binding protein 3, Octamer-binding protein 4, Octamer-binding transcription factor 3, Oct-3, Oct-4, OTF-3

反应种属:Human, Mouse
抗原名称:POU5F1
应用:WB, IF/ICC, IP

详细信息

免疫原The exact immunogen used to generate this antibody is proprietary information.
宿主/亚型Rabbit / IgG
抗体类型Polyclonal
产品形式Liquid
纯化方式Affinity purification Protein A
储存缓冲液pH: 7.4 Preservative: 0.02% Sodium azide Constituents: PBS, 1% BSA
储存条件运输条件: Blue Ice 推荐的短期储存时间: 1-2 weeks 推荐的短期储存条件: +4°C 推荐的长期储存条件: -20°C 储存信息: Avoid freeze / thaw cycle
无载体蛋白No

特异性

Previous batches of ab19857 have worked well in IHC, but recent batches of this antibody are showing non-specific staining on day 6 mouse testis in our lab (as of Nov 2016). Replenishment batches of our polyclonal antibody, ab19857 are tested in WB. Previous batches were additionally validated in ICC/IF and IP. These applications are still expected to work and are covered by our Abpromise guarantee. You may also be interested in our alternative recombinant antibody, ab181557.

背景信息

Product Specifications Anti-Oct4 antibody (ab19857) is a rabbit polyclonal antibody and is validated for use in ICC/IF, IP, WB in human, mouse samples. Anti-Oct4 antibody (ab19857) specifically detects Oct4 (UniProt ID: Q01860; Molecular weight: 39kDa) and is sold in 100 µg selling sizes. Quality and Validation Abcam's high quality validation processes ensure Anti-Oct4 antibody (ab19857) has high sensitivity and specificity. Anti-Oct4 antibody (ab19857) has been cited over 566 times in peer reviewed journals and is trusted by the scientific community. Anti-Oct4 antibody (ab19857) has 41 independent reviews from customers.

文献引用 (527)

VMAT2 dysfunction impairs vesicular dopamine uptake, driving its oxidation and α-synuclein pathology in DJ-1-linked Parkinson's neurons.

VMAT2 功能障碍会损害囊泡多巴胺的摄取,从而导致 DJ-1 相关的帕金森神经元中多巴胺的氧化和 α-突触核蛋白病理。

Heger Leonie M, Gubinelli Francesco, Huber Andreas J, Cardona-Alberich Aida, Rovere Matteo, Matti Ulf, Müller Stephan A, Nagaraja Sankarshana R, Jaschkowitz Lena, Schifferer Martina, Wurst Wolfgang, Lichtenthaler Stefan F, Behrends Christian, Sambandan Sivakumar, Burbulla Lena F

LncRNA ELFN1-AS1 maintains the stemness of colorectal cancer by preventing ubiquitinated degradation of the hnRNPA1 protein.

LncRNA ELFN1-AS1 通过阻止 hnRNPA1 蛋白的泛素化降解来维持结直肠癌的干性。

Wang Huiling, Du Fei, Zhang Hantao, Li Junshu, Xiong Qi, Zhang Yong, Chen Na, Liu Yi, Guo Siqi, Xie Qian, Dai Lei, Deng Hongxin

Comparing the impact of sample multiplexing approaches for single-cell RNA-sequencing on downstream analysis using cerebellar organoids.

比较单细胞 RNA 测序样本多重化方法对小脑类器官下游分析的影响。

Sarieva Kseniia, Kagermeier Theresa, Lysenkov Vladislav, Castagnetti Francesco, Yentuer Zeynep, Becker Katharina, Matilainen Julia, Casadei Nicolas, Mayer Simone

Bi-allelic variants in BCAT1 impair mitochondrial function and are associated with a candidate neurometabolic disorder

BCAT1基因的双等位基因变异会损害线粒体功能,并与一种候选神经代谢疾病相关。

Brianna L DiSanza,Giulia S Porcari,Livia Sertori Finoti,Leonardo Ramos-Rodriguez,Devin M Burris,Justin A McDonough,Gang Ning,Grace Fagan,Guy T Helman,Erin Weiss,Ryan J Taft,Amy Pizzino,Matthew T Whitehead,Amy Waldman,Cas Simons,Xilma Ortiz-Gonzalez,William C Skarnes,Adeline Vanderver,Elizabeth J Bhoj,Rebecca C Ahrens-Nicklas

Spatial relationships between vinculin tension and actin at cell adhesions define cell colony positioning and identity.

细胞粘附处黏着斑蛋白张力与肌动蛋白之间的空间关系决定了细胞群落的定位和特性。

Nagle Abigail, Leung Cherry, Karbassi Elaheh, Young Jessica, Regnier Michael, Davis Jennifer

Generation of induced pluripotent stem cells from a patient with CHARGE syndrome with athymia, harboring a heterozygous mutation in CHD7.

从患有 CHARGE 综合征且无胸腺的患者体内生成诱导多能干细胞,该患者携带 CHD7 杂合突变。

Zhao Jin, Hu Rong, Lai Kuan Chen, Liu Yaling, Carmichael Gordon G, Martin Donna M, Lai Laijun

A human-specific enhancer fine-tunes radial glia potency and corticogenesis.

人类特异性增强子可微调放射状胶质细胞的潜能和皮质发育

Liu Jing, Mosti Federica, Zhao Hanzhi T, Lollis Davoneshia, Sotelo-Fonseca Jesus E, Escobar-Tomlienovich Carla F, Musso Camila M, Mao Yiwei, Massri Abdull J, Doll Hannah M, Moss Nicole D, Sousa Andre M M, Wray Gregory A, Schmidt Ewoud R E, Silver Debra L

c-JUN: a chromatin repressor that limits mesoderm differentiation in human pluripotent stem cells

c-JUN:一种染色质抑制因子,可限制人类多能干细胞中胚层分化

Ran Zhang ,Guihuan Li ,Qi Zhang ,Zhenhua Wang ,Dan Xiang ,Xiaofei Zhang ,Jiekai Chen ,Andrew P Hutchins ,Dajiang Qin ,Huanxing Su ,Duanqing Pei ,Dongwei Li

Molecular and epistatic interactions between pioneer transcription factors shape nucleosome dynamics and cell differentiation.

先锋转录因子之间的分子和上位性相互作用塑造了核小体动力学和细胞分化。

Coux Rémi-Xavier, Dubois Agnès, Chervova Almira, Gonzalez Inma, Vandormael-Pournin Sandrine, Cohen-Tannoudji Michel, Navarro Pablo

Enhanced hybridization-proximity labeling discovers protein interactomes of single RNA molecules.

增强型杂交邻近标记技术可发现单个 RNA 分子的蛋白质相互作用组。

Yap Karen, Chung Tek Hong, Hedges Erin C, Nishimura Agnes L, Shaw Christopher E, Makeyev Eugene V
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