Anti-Collagen II antibody [EPR12268] (Ab188570)

Collagen alpha-1(II) chain, Alpha-1 type II collagen, COL2A1

反应种属:Human, Rat
抗原名称:COL2A1
应用:WB

详细信息

免疫原The exact immunogen used to generate this antibody is proprietary information.
宿主/亚型Rabbit / IgG
抗体类型Monoclonal
产品形式Liquid
纯化方式Affinity purification Protein A
储存缓冲液pH: 7.2 - 7.4 Preservative: 0.01% Sodium azide Constituents: PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA
储存条件运输条件: Conditional Ambient 推荐的短期储存时间: 1-2 weeks 推荐的短期储存条件: +4°C 推荐的长期储存条件: -20°C 储存信息: Avoid freeze / thaw cycle
无载体蛋白No

背景信息

Patented technology Our RabMAb ® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb ® patents. What are the advantages of a recombinant monoclonal antibody? This product is a recombinant monoclonal antibody, which offers several advantages including - High batch-to-batch consistency and reproducibility - Improved sensitivity and specificity - Long-term security of supply - Animal-free batch production For more information, read more on recombinant antibodies.

文献引用 (131)

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利用压电刺激调节PI3K-AKT信号通路促进椎间盘再生。

Organic di-selenide hydrogel microspheres for multimodal treatment of osteoarthritis.

用于骨关节炎多模式治疗的有机二硒化物水凝胶微球。

Synovial inflammatory macrophage-derived extracellular vesicles exacerbate cartilage lesions with a FMRP-selectively sorted manner in osteoarthritis

在骨关节炎中,滑膜炎症巨噬细胞来源的细胞外囊泡以FMRP选择性分选的方式加剧软骨损伤

Shu Zhao,Jian Wang,Mengxin Xue,Baitong Wu,Lanyue Sheng,Yi Wen,Guangming Wang,Jianxing Song,Dajiang Du,Jun Xu

Integrated analysis of bulk RNA and single-cell RNA sequencing data reveals potential biomarkers and immune infiltrates associated with N7-methylguanosine in osteoarthritis.

对大量 RNA 和单细胞 RNA 测序数据的综合分析揭示了与骨关节炎中 N7-甲基鸟苷相关的潜在生物标志物和免疫浸润。

Sun Hong, Chen Kunhao, Xiong Zhilin, Zhuang Yong, Liu Miao, Ning Xu, Yang Hua

The protective up-regulation of metallothionein-2A in intervertebral disc degeneration inhibits nucleus pulposus cell ferroptosis through activation of the PI3K/AKT/mTOR pathway.

椎间盘退变中金属硫蛋白-2A的保护性上调通过激活PI3K/AKT/mTOR通路抑制髓核细胞铁死亡。

Cai Hao, Zheng Huo-Liang, Chen Qi-Zhu, Song Shao-Kuan, Yang Bing-Yi, Wang Yong, Deng Hui, Mardan Muradi, Lu Ze-Yu, Chen Peng-Bo, Xu Qing-Yin, Li Bo, Jiang Lei-Sheng, Zheng Xin-Feng, Jiang Sheng-Dan

Identifying druggable gene-related biomarkers in intervertebral disc degeneration through transcriptome sequencing and mendelian randomization analysis.

通过转录组测序和孟德尔随机化分析鉴定椎间盘退变中可药物靶向的基因相关生物标志物。

Therapeutic effect of edaravone on osteoarthritis: targeting NRF2 signaling and mitochondrial function.

依达拉奉对骨关节炎的治疗作用:靶向 NRF2 信号传导和线粒体功能

Jiang Chao, Gong Yuhang, Wu Xinyu, Chen Jiangjie, Chen Yiyu, Chen Jingyao, Tang Fang, Fang Zhiyu, Bao Yuxuan, Ye Jiajing, Wang Zhangfu, Hong Zhenghua

PPARγ controls ESCRT-dependent fibroblast-like synoviocyte exosome biogenesis and alleviates chondrocyte osteoarthritis mediated by exosomal ANXA1.

PPARγ 控制 ESCRT 依赖的成纤维细胞样滑膜细胞外泌体生物发生,并缓解由外泌体 ANXA1 介导的软骨细胞骨关节炎

Jia Shuangshuo, Yang Yue, Liu Jiabao, Wang Ziyuan, Bai Lunhao

S-propargyl-cysteine attenuates temporomandibular joint osteoarthritis by regulating macrophage polarization via Inhibition of JAK/STAT signaling.

S-丙炔基半胱氨酸通过抑制JAK/STAT信号通路调节巨噬细胞极化,从而减轻颞下颌关节骨关节炎

Cai Wenyi, Wu Antong, Lin Zhongxiao, Cao Wei, Pathak Janak L, Jaspers Richard T, Li Rui, Li Xin, Zheng Kaihan, Lin Yufu, Zhou Na, Zhang Xin, Zhu Yizhun, Zhang Qingbin

circNR3C2 promotes chondrogenic differentiation and cartilage repair of human adipose-derived stem cells via the hsa-miR-647/SOX9 pathway.

circNR3C2 通过 hsa-miR-647/SOX9 通路促进人类脂肪来源干细胞的软骨分化和软骨修复。

Hou Dabiao, Wang Huajun, Guo Hao, Luo Dongbin, Zheng Xiaofei, Luo Simin
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