Anti-c-Fos antibody - BSA free (Ab190289)

G0S7, FOS, Protein c-Fos, Cellular oncogene fos, G0/G1 switch regulatory protein 7, Proto-oncogene c-Fos, Transcription factor AP-1 subunit c-Fos

反应种属:Human, Mouse, Rat
抗原名称:FOS
应用:WB, IHC, IF/ICC, IHCFl

详细信息

免疫原Recombinant Full Length Protein corresponding to Human FOS. P01100
宿主/亚型Rabbit / IgG
抗体类型Polyclonal
产品形式Liquid
纯化方式Affinity purification Protein A
储存缓冲液Preservative: 0.033% Sodium azide Constituents: PBS, 49.9% Glycerol (glycerin, glycerine)
储存条件运输条件: Blue Ice 推荐的短期储存时间: 1-2 weeks 推荐的短期储存条件: +4°C 推荐的长期储存条件: -20°C 储存信息: Avoid freeze / thaw cycle
无载体蛋白No

背景信息

Anti-c-Fos antibody - BSA free (ab190289) is a rabbit polyclonal antibody and is validated for use in ICC/IF, IHC-FrFl, IHC-P and WB. Anti-c-Fos antibody - BSA free (ab190289) was first used in a scientific publication in 2015 and has been cited over 216 times in peer reviewed journals. It's performance in IHC in mouse and rat samples is trusted by the scientific community. Abcam's high quality validation processes ensure Anti-c-Fos antibody - BSA free (ab190289) has high sensitivity and specificity. Anti-c-Fos antibody - BSA free (ab190289) has 8 independent reviews from customers. Anti-c-Fos antibody - BSA free (ab190289) specifically detects c-Fos (UniProt ID: P01100; Molecular weight: 41kDa) and is sold in 100 µL selling sizes. c-Fos is an immediate-early gene widely used in neuro research for its role as a marker of neuronal activation. It is rapidly expressed in response to various stimuli, making it an excellent indicator of neuronal activity and functional mapping. Researchers use c-Fos to study brain activity patterns, synaptic plasticity and the effects of drugs or other interventions on the central nervous system, making it essential for understanding dynamic changes in brain function.

文献引用 (413)

Altered trafficking of Kv1-Kvβ2 leads to neuronal hyperexcitability and memory deficits in amyloid-β pathology.

Kv1-Kvβ2 转运异常导致淀粉样蛋白β病理中的神经元过度兴奋和记忆缺陷。

Cho Young-Sin, Kim Seo-Hyun, Ryu Shin-Hyeon, Chung Chaelin, Lee Nahyun, Kim Namhoon, Jeong Muhah, Kim Youngwon, Gwak Jimin, Choi Se-Young, Saido Takaomi, Jung Yong-Keun

Restoring early postnatal synaptic dysregulation rescues motor neuron degeneration in a mouse model of Spinal and Bulbar Muscular Atrophy.

恢复早期出生后突触功能障碍可以挽救脊髓延髓肌萎缩症小鼠模型中的运动神经元退化。

Hirunagi Tomoki, Sahashi Kentaro, Iida Madoka, Onodera Kazunari, Yokoi Satoshi, Ogura Yosuke, Tohnai Genki, Sakakibara Kenji, Maeda Kentaro, Bennett C Frank, Okada Yohei, Katsuno Masahisa

Near-infrared light-activated lidocaine microneedle patch for rapid local anesthesia.

近红外光激活利多卡因微针贴片,用于快速局部麻醉。

Wang Shuailei, Zhao Ze Qiang, He Yumiao, Chen Bo Zhi, Liu Hongju, Guo Xin Dong, Huang Yuguang

Physical activity promotes gut adaptation, nutrient responsiveness, and sensitivity to gut peptides in male mice.

体育锻炼可以促进雄性小鼠的肠道适应性、营养反应性和对肠道肽的敏感性。

The GluA1 cytoplasmic tail regulates intracellular AMPA receptor trafficking and synaptic transmission onto dentate gyrus GABAergic interneurons, gating response to novelty.

GluA1 胞质尾调节细胞内 AMPA 受体运输和突触传递到齿状回 GABA 能中间神经元,从而控制对新事物的反应。

Leana-Sandoval Gerardo, Madrid Alexis, Kolli Ananth V, Chinn Carlene A, Sandoval Matthew A, Lo Iris, Alizo Vera Vanessa, Simms Jeffrey, Wood Marcelo A, Díaz-Alonso Javier

Silmitasertib, an FDA-designated orphan CK2 inhibitor, ameliorates neuropathology and motor dysfunction in a Huntington's disease mouse model.

Silmitasertib 是一种 FDA 指定的孤儿药 CK2 抑制剂,可改善亨廷顿病小鼠模型中的神经病理学和运动功能障碍。

Pelzel Ross J, Herbst Miaya, Rozema Nicholas B, Solem Melissa A, Gomez-Pastor Rocio

Protein kinase C epsilon deletion in AgRP neurons modulates hypothalamic glucose sensing and improves glucose tolerance in mice.

AgRP 神经元中蛋白激酶 C ε 的缺失会调节小鼠下丘脑葡萄糖感知并改善葡萄糖耐受性。

Brandon Amanda E, Yan Chenxu, Zhang Xuan, Ip Chi Kin, Gao Zhongmin, Lee Nicola J, Marian Oana C, Perez Alex, Don Anthony S, Herzog Herbert, Small Lewin, Shi Yan-Chuan, Schmitz-Peiffer Carsten

Long-term social isolation during adolescence exacerbated cardiac dysfunction after myocardial infarction.

青少年时期长期的社会隔离加剧了心肌梗塞后的心脏功能障碍。

Yao Yuan, Wang Anhui, Di Chang, Guo Dan, Zhang Shiya, Zong Runzhe, Qi Rong, Han Ying

The acid-sensing ion channel 1a modulates anxiety- and depression-related behaviors via its influencing on the activity of corticotropin-releasing hormone-expressing neurons in the hypothalamic paraventricular nucleus in male mice.

酸敏感离子通道 1a 通过影响雄性小鼠下丘脑室旁核中表达促肾上腺皮质激素释放激素的神经元的活动来调节焦虑和抑郁相关的行为。

Yue Jiayin, Zhang Qilun, Wang Mengyuan, Yao Xuelin, Wang Mengtian, Liu Ling, Huang Zhaohuan, Xing Yan, Yan Jinling, Yan Zihui, Song Xing-Lei, Wang Wei

Somatosensory cortical progesterone receptor signaling regulates the episodic to chronic migraine transformation.

体感皮层孕酮受体信号传导调节发作性偏头痛向慢性偏头痛的转变。

Joshi Suchitra, Williamson John, Etcheberrigaray Daniel, Goodkin Howard P, Kapur Jaideep
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