Anti-TLR4 antibody [76B357.1] (Ab22048)

CD284, Toll-like receptor 4, hToll, TLR4

反应种属:Human, Mouse, Rat, Pig
抗原名称:TLR4
应用:IHC, ELISA, FCM, IF/ICC, ICC

用户验证的应用

推荐稀释比例

  • Flow Cyt (Intra)1 µg for 10^6 Cells Methanol or paraformaldehyde fixed cells. ab170192 - Mouse monoclonal IgG2b, is suitable for use as an isotype control with this antibody.

详细信息

免疫原Synthetic Peptide within Human TLR4 aa 100-200 conjugated to Keyhole Limpet Haemocyanin. The exact immunogen used to generate this antibody is proprietary information. O00206
宿主/亚型Mouse / IgG2b
抗体类型Monoclonal
全称Anti-TLR4 antibody [76B357.1]
产品形式Liquid
储存缓冲液pH: 7.4 Preservative: 0.05% Sodium azide Constituents: PBS, 0.05% BSA
储存条件运输条件: Blue Ice 推荐的短期储存时间: 1-2 weeks 推荐的短期储存条件: +4°C 推荐的长期储存条件: -20°C 储存信息: Avoid freeze / thaw cycle
纯化方式Affinity purification Protein G

背景信息

Product Specifications Anti-TLR4 antibody [76B357.1] (ab22048) is a mouse monoclonal antibody and is validated for use in ELISA, Flow Cyt (Intra), ICC, ICC/IF, IHC-Fr, IHC-P in human, mouse, pig, rat samples. Anti-TLR4 antibody [76B357.1] (ab22048) specifically detects TLR4 (UniProt ID: O00206; Molecular weight: 93kDa) and is sold in 100 µg selling sizes. Quality and Validation Abcam's high quality validation processes ensure Anti-TLR4 antibody [76B357.1] (ab22048) has high sensitivity and specificity. Anti-TLR4 antibody [76B357.1] (ab22048) has been cited over 297 times in peer reviewed journals and is trusted by the scientific community. Anti-TLR4 antibody [76B357.1] (ab22048) has 26 independent reviews from customers.

文献引用 (291)

Immune-activating PTL/nanowire composite coating on Ti surface enables macrophage-driven bacterial clearance and osseointegration.

在钛表面涂覆免疫激活PTL/纳米线复合涂层,可实现巨噬细胞驱动的细菌清除和骨整合。

Hang Ruiyue, Chen Huanming, Yang Liwei, Di Ruoyu, Zhao Yuyu, Yao Runhua, Yao Xiaohong, Wang Huaiyu, Xiao Yin, Hang Ruiqiang

Maternal gut microbiota mediates prenatal stress-induced fetal blood‒brain barrier dysfunction.

母体肠道菌群介导产前应激引起的胎儿血脑屏障功能障碍。

Wang Xuanping, Zhou Fang-Yue, Wu Ting, Duan Chenchi, Luo Xukai, Meng Yicong, Huang He-Feng, Wu Yan-Ting

Targeting the intestinal TLR4-GABA(A) axis to promote stroke recovery.

靶向肠道 TLR4-GABA(A) 轴以促进中风恢复。

Huang Xiaoqi, Chen Shengnan, Zhang Wen, Li Jie, Yang Siqi, Zhou Lang, Zhou Hongwei, Xu Kaiyu

Microbe-associated molecular patterns differentially mediate carcinogenic alterations of the breast tissue in the context of obesity.

微生物相关分子模式在肥胖背景下对乳腺组织的致癌性改变具有不同的介导作用。

Gaber Mohamed, Moulden Lauren M, Wilson Adam S, Payne Valerie, Holmes Julia, Neary Kayla, Peoples Abigail, Duet Mary L, Katz Adam J, Vidi Pierre-Alexandre, Cook Katherine L

Porcine decellularized nerve matrix hydrogel attenuates neuroinflammation after peripheral nerve injury by inhibiting the TLR4/MyD88/NF-κB axis

猪源脱细胞神经基质水凝胶通过抑制TLR4/MyD88/NF-κB轴减轻周围神经损伤后的神经炎症。

Rui Li ,Jianquan Liu ,Liuxun Li ,Guotian Luo ,Xinrong Yuan ,Shichao Shen ,Yongpeng Shi ,Jianlong Wu ,Bin Yan ,Lei Yang

Sex-specific metabolic and microbial remodeling in a rotenone-induced rat model of Parkinson's disease following nicotine administration.

在尼古丁给药后,鱼藤酮诱导的帕金森病大鼠模型中存在性别特异性的代谢和微生物重塑。

Ni Zhen, Wang Gaoge, Li Qian, Wu Xiaqing, Song Zheng, Yu Hao, Yu Pengpeng, Chen Yibo, Li Lixiang, Chen Huan, Hou Hongwei, Hu Qingyuan

Oral Administration of Crocus sativus Tepals Extract Restores High-Fat Diet-Induced Gut Dysbiosis and Modulates Intestinal Inflammation and Hepatic Lipid Metabolism.

口服番红花花瓣提取物可恢复高脂饮食引起的肠道菌群失调,并调节肠道炎症和肝脏脂质代谢。

Bursać Biljana, Vratarić Miloš, Gligorovska Ljupka, Bellachioma Luisa, Teofilović Ana, Vojnović Milutinović Danijela, Morresi Camilla, Damiani Elisabetta, Bacchetti Tiziana, Djordjevic Ana

Pomiferin protects against sepsis-associated acute liver and kidney injury via inhibition of NF-κB activation, oxidative stress, and cytochrome-c.

Pomiferin 通过抑制 NF-κB 活化、氧化应激和细胞色素 c 来保护机体免受脓毒症相关的急性肝肾损伤。

Alhilal Mohammad, Erol Huseyin Serkan, Yildirim Serkan, Koc Murat, Alhilal Suzan, Dereli Esra, Karaarslan Tuba, Senocak Esra Aktas, Bozkurt Ilyas, Keles Osman Nuri, Halici Mesut Bunyami

Increased Toll-Like Receptor-4 Signalling in Breast Tissue of High Fibroglandular Density.

高纤维腺体密度乳腺组织中 Toll 样受体 4 信号传导增强。

Heydarlou Hanieh, Hodson Leigh J, Dasari Pallave, Smith Eric, Ingman Wendy V

Adolescent adversity persistently induces proinflammatory HMGB1 signaling and disrupts the basal forebrain cholinergic system in female rats.

青春期逆境持续诱导促炎性 HMGB1 信号传导,并破坏雌性大鼠的基底前脑胆碱能系统。

Ross Hayley, Adelman Makayla, Castillo Juan E, Walker Ann, Latham Joseph, Qin Liya, Macht Victoria, Crews Fulton T, Vetreno Ryan P
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