Anti-ALKBH5 antibody [EPR18958] (Ab195377)

ABH5, OFOXD1, ALKBH5, RNA demethylase ALKBH5, Alkylated DNA repair protein alkB homolog 5, Alpha-ketoglutarate-dependent dioxygenase alkB homolog 5

反应种属:Human, Mouse, Rat
抗原名称:ALKBH5
应用:WB, IHC

详细信息

免疫原The exact immunogen used to generate this antibody is proprietary information.
宿主/亚型Rabbit / IgG
抗体类型Monoclonal
产品形式Liquid
纯化方式Affinity purification Protein A
储存缓冲液pH: 7.2 - 7.4 Preservative: 0.01% Sodium azide Constituents: PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA
储存条件运输条件: Conditional Ambient 推荐的短期储存时间: 1-2 weeks 推荐的短期储存条件: +4°C 推荐的长期储存条件: -20°C 储存信息: Avoid freeze / thaw cycle
无载体蛋白No

背景信息

What is this antibody validated in? Anti-ALKBH5 antibody [EPR18958] (ab195377) is a rabbit recombinant monoclonal antibody and is validated for use in Western Blot (WB), Immunohistochemistry (IHC-P) in Human, Mouse, Rat samples. What is the molecular weight of ALKBH5? Anti-ALKBH5 [EPR18958] (ab195377) specifically detects a band for ALKBH5 (UniProt: Q6P6C2) at a molecular weight of 44kDa. Trusted by the scientific community Anti-ALKBH5 [EPR18958] (ab195377) was first used in a scientific publication in 2018 and has been cited over 60 times in peer-reviewed journals. Specificity confirmed The specificity of Anti-ALKBH5 antibody [EPR18958] (ab195377) has been confirmed by Western blot testing in ALKBH5 Knockout HEK293T cell line, ab266762. Other related products We have a range of other formats of antibody clone [EPR18958] also available for your convenience: ab195377, Carrier free - ab234528, Alexa Fluor® 647 - ab245891 Patented technology Our RabMAb ® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb ® patents. What are the advantages of a recombinant monoclonal antibody? This product is a recombinant monoclonal antibody, which offers several advantages including - High batch-to-batch consistency and reproducibility - Improved sensitivity and specificity - Long-term security of supply - Animal-free batch production For more information, read more on recombinant antibodies. Trial sizes available! Test your antibody or perform pre-screening before committing to a larger quantity. Sold in 20µl. Discover our selection of trial-size antibodies.

文献引用 (117)

Reversible ALKBH5 cytosolic aggregation accelerates cellular senescence.

ALKBH5胞质可逆聚集加速细胞衰老。

ALKBH5 facilitates Srgn stability via m6A demethylation to disrupt blood-testis barrier integrity in the high-fat diet mice.

ALKBH5 通过 m6A 去甲基化促进 Srgn 的稳定性,从而破坏高脂饮食小鼠的血睾屏障完整性。

Du Tian, Yao Liangyu, Wang Wenhua, Li Zhou, Dong Jie, Zhou Zheng, Shi Chengyu, Ge Xie, Ma Rujun, Chen Li, Xiang Yijian, He Zhaowanyue, Zheng Lu, Xu Yao, Cao Chun, Jing Jun, Ma Jinzhao, Yao Bing

Integrative multi-omic profiling of the chronically hypoxic heart: focus on m(6)A and m(6)Am epitranscriptomic regulation.

慢性缺氧心脏的整合多组学分析:重点关注 m(6)A 和 m(6)Am 表观转录组调控。

Hlavackova Marketa, Benak Daniel, Sotakova-Kasparova Dita, Holzerova Kristyna, Skriba Anton, Simonova Anna, Cahova Hana, Kobets Tatyana, Jancova Tereza, Kolar Frantisek

Tamoxifen differentially modulates endometrial hyperplasia via wild-type and mutant p53 regulation of the ALKBH5-REG1A axis.

他莫昔芬通过野生型和突变型 p53 对 ALKBH5-REG1A 轴的调控,差异性地调节子宫内膜增生。

Wang Rencheng, Ji Jianhua, Liu Lei

Diabetic Kidney Disease Progression Alleviated in Mice by ALKBH5-Mediated UC-MSCs-Derived Exosomes That Inhibit TRAF6 m6A Modification and Promote M2 Macrophage Polarisation.

ALKBH5介导的UC-MSC衍生外泌体抑制TRAF6 m6A修饰并促进M2巨噬细胞极化,从而缓解小鼠糖尿病肾病进展。

Li Lei, Liu Hongmei, Wang Huanhuan, Mao Yu, Song Lige, Kang Zhiqiang

ALKBH5-mediated m6A demethylation of TXNDC5 drives malignant progression in gastric cancer.

ALKBH5 介导的 TXNDC5 m6A 去甲基化驱动胃癌的恶性进展。

Identification and validation of PANoptosis-related genes in ankylosing spondylitis.

强直性脊柱炎中PANoptosis相关基因的鉴定和验证。

METTL3/ALKBH5-Mediated N6-Methyladenosine Modification Drives Macrophage M1 Polarization via the SLC15A3-TASL-IRF5 Signaling Axis in Psoriasis.

METTL3/ALKBH5介导的N6-甲基腺苷修饰通过SLC15A3-TASL-IRF5信号轴驱动银屑病巨噬细胞M1极化。

Huang Tao, Chen Shijun, Ding Ke, Yuan Liyan, Lv Weiqi, Chen Kechen, Liu Yuchen, Ma Dongzhao, Zhang Xin, Wang Xiaobo, Luo Guanzheng, Yang Bin, Lin Ying, Rong Zhili

FTO regulates ELK3-mediated metabolic rewiring and represents a unique therapeutic target in T cell leukemia

FTO调控ELK3介导的代谢重编程,是T细胞白血病中一个独特的治疗靶点。

Hao Huang,Xinlu Li,Jinlian Luo,Chuan Gao,Mengjie Yang,Jin Xu,Ting Xie,Zhi Chen,Donghai Wang,Yuan Wang,Hua-Bing Li,Jinyan Huang,Yu Liu,Haojian Zhang,Panagiotis Ntziachristos,Yun Zhao,Guoliang Qing,Hudan Liu

Follicle-stimulating hormone promotes EndMT in endothelial cells by upregulating ALKBH5 expression.

促卵泡激素通过上调ALKBH5表达促进内皮细胞的EndMT

Li Ping, Xiang Yixiao, Wei Jinzhi, Xu Xingyan, Wang Jiale, Yu Haowei, Li Xiaosa, Lin Huiping, Fu Xiaodong
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