用户验证的应用
推荐稀释比例
- Flow Cyt0.1-1 µg for 10^6 Cells ab18536 - Rat monoclonal IgG2b, is suitable for use as an isotype control with this antibody.
详细信息
背景信息
ab22378 is not expected to work in standard western blots, under denaturing conditions, or in IHC on formalin-fixed tissue. To our knowledge, ab22378 will only stain frozen sections or fresh cells, and will only immunoprecipitate the antigen from cell lysates in mild detergents such as NP40 or Triton-X100. Want a custom formulation? This antibody clone is manufactured by Abcam. If you require a custom buffer formulation or conjugation for your experiments, please contact orders@abcam.com
文献引用 (93)
Attenuated Salmonella secreting interleukin-21 activates T-cells and induces anti-tumor effects
减毒沙门氏菌分泌白细胞介素-21，可激活T细胞并诱导抗肿瘤效应
Sympathetic nerve aggravates autoimmune skin disease via NE-adrenergic receptor axis: Neuroimmune cross-talk insights from vitiligo.
交感神经通过 NE-肾上腺素能受体轴加重自身免疫性皮肤病：来自白癜风的神经免疫交叉对话见解。
Tumor-to-endothelium mitochondrial transfer licenses endothelial cells for CD8(+) T cell recognition via mitochondrial neoantigen presentation.
肿瘤细胞向内皮细胞的线粒体转移通过线粒体新抗原呈递，使内皮细胞能够被 CD8(+) T 细胞识别。
Mutant p53 exploits enhancers to elevate immunosuppressive chemokine expression and impair immune checkpoint inhibitors in pancreatic cancer
突变型p53利用增强子提高免疫抑制性趋化因子的表达，并削弱胰腺癌中的免疫检查点抑制剂的作用。
The tumor-sentinel lymph node immuno-migratome reveals CCR7⁺ dendritic cells drive response to sequenced immunoradiotherapy
肿瘤前哨淋巴结免疫迁移组学分析表明，CCR7⁺树突状细胞驱动对序贯免疫放射疗法的反应。
Tumorous cholesterol biosynthesis curtails anti-tumor immunity by preventing MTOR-TFEB-mediated lysosomal degradation of CD274/PD-L1.
肿瘤胆固醇生物合成通过阻止 MTOR-TFEB 介导的 CD274/PD-L1 溶酶体降解来抑制抗肿瘤免疫。
The MLL3/GRHL2 complex regulates malignant transformation and anti-tumor immunity in squamous cancer
MLL3/GRHL2复合物调控鳞状细胞癌的恶性转化和抗肿瘤免疫。
Targeting YTHDF2 with pH-responsive siRNA nanoparticles suppresses MYC m6A modification and restores antitumor immunity in hepatocellular carcinoma
利用pH响应性siRNA纳米颗粒靶向YTHDF2可抑制MYC m6A修饰并恢复肝细胞癌的抗肿瘤免疫力。
From foe to friend: Rewiring oncogenic pathways through artificial selenoprotein to combat immune-resistant tumor.
从敌人到朋友：通过人工硒蛋白重塑致癌通路以对抗免疫抵抗性肿瘤。
Dimethyl itaconate suppresses dendritic cell and CD8(+) T cell responses to halt vitiligo.
衣康酸二甲酯抑制树突状细胞和 CD8(+) T 细胞反应，从而阻止白癜风的发生。
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