Anti-Fatty Acid Synthase antibody (Ab22759)

Fatty acid synthase, Type I Fatty Acid Synthase

反应种属:Human, Mouse, Rat
抗原名称:FASN
应用:WB, IHC, IF/ICC

详细信息

免疫原The exact immunogen used to generate this antibody is proprietary information.
宿主/亚型Rabbit / IgG
抗体类型Polyclonal
产品形式Liquid
纯化方式Affinity purification Immunogen
储存缓冲液pH: 7.4 Preservative: 0.02% Sodium azide Constituents: PBS, 1% BSA
储存条件运输条件: Blue Ice 推荐的短期储存时间: 1-2 weeks 推荐的短期储存条件: +4°C 推荐的长期储存条件: -20°C 储存信息: Avoid freeze / thaw cycle

特异性

From Jan 2024, QC testing of replenishment batches of this polyclonal changed. All tested and expected application and reactive species combinations are still covered by our Abcam product promise. However, we no longer test all applications. For more information on a specific batch, please contact our Scientific Support who will be happy to help. You may also be interested in our alternative recombinant antibody, ab128870.

背景信息

What is this antibody validated in? Anti-Fatty Acid Synthase antibody (ab22759) is a rabbit polyclonal antibody and is validated for use in Western Blot (WB) in Human, Mouse, Rat samples. What is the molecular weight of Fatty Acid Synthase? Anti-Fatty Acid Synthase (ab22759) specifically detects a band for Fatty Acid Synthase (UniProt: P49327) at a molecular weight of 273kDa. Trusted by the scientific community Anti-Fatty Acid Synthase (ab22759) was first used in a scientific publication in 2006 and has been cited over 110 times in peer-reviewed journals. Reviewed by scientists Anti-Fatty Acid Synthase (ab22759) has over 10 independent reviews from customers. Specificity confirmed The specificity of Anti-Fatty Acid Synthase antibody (ab22759) has been confirmed by Western blot testing in Fasn Knockout HAP1 cells.

文献引用 (124)

Identification of ACBP as a potential target in ciliopathic obesity through multi-omics network analysis.

通过多组学网络分析确定 ACBP 为纤毛病性肥胖的潜在靶点。

Hepatic glutathione depletion ameliorates MASLD through selective protein oxidation and inhibition of lipogenesis.

肝脏谷胱甘肽耗竭可通过选择性蛋白质氧化和抑制脂肪生成来改善 MASLD。

Liu Xiang-Yu, Wang Guoxiao, Yu Yingying, Xiao Haopeng, Oh-Hashi Kentaro, Shi Xu, Zheng Shuning, Gerszten Robert, Kahn C Ronald

Modeling embryonic heart vascular plexus development and sympathetic innervation on a human heart organoid.

在人类心脏类器官上模拟胚胎心脏血管丛发育和交感神经支配。

Branco Mariana A, Marzec Jacek, Nunes Mafalda Marques, Bica Marta, Rayagra Ana Luísa, Tenreiro Miguel F, Cabral Joaquim M S, Diogo Maria Margarida

High-dose taurine supplementation exacerbates alcohol-associated liver disease by inducing gut microbiota dysbiosis and bile acid dysregulation in mice.

高剂量牛磺酸补充剂会通过诱导小鼠肠道菌群失调和胆汁酸失调,加剧酒精相关性肝病。

Pei Jingdan, Chen Lixian, Pushparaj Rahul, Huang Panpan, Pan Guihua, Sun Chunbao, Gao Xing, Zhang Lihua, Manirujjaman Md, Huang Chiung-Kuei, Ting Peng-Sheng, Deng Zhongbin, Chen Shaoyu, Zhang Xiang, Vatsalya Vatsalya, McClain Craig J, Feng Wenke

Portal vein-enriched metabolites as intermediate regulators of the gut microbiome in insulin resistance.

门静脉富集代谢物作为肠道微生物群在胰岛素抵抗中的中间调节因子。

Muñoz Vitor Rosetto, Moreau Francois, Soto Marion, Watanabe Yoshiyuki, Pham Loc-Duyen, Zhong Jimmy, Zimmerman Sam, Brandao Bruna B, Girdhar Khyati, Avila Julian, Pan Hui, Dreyfuss Jonathan M, Mi Michael Y, Gerszten Robert E, Altindis Emrah, Kostic Aleksandar, Clish Clary B, Kahn C Ronald

Hepatic ENTPD5 Is Critical for Maintaining Metabolic Homeostasis and Promoting Brown Adipose Tissue Thermogenesis.

肝脏ENTPD5对于维持代谢稳态和促进棕色脂肪组织产热至关重要。

Rebaudioside D and M, the next-generation sugar substitutes, do not exacerbate metabolic dysfunction in high-fat diet mice.

新一代糖替代品莱鲍迪苷 D 和 M 不会加剧高脂饮食小鼠的代谢功能障碍

Lim Sangyi, Park Min-Jung, Yoon Ki-Nam, Lee Junhyeong, Matienzo Merc Emil, Hong Seong-Jin, Kim Keon, Baek Yeong-Bin, Lee Chang-Min, Kim Young-Min, Park Bu-Soo, Kim Dong-Il

Comparative study of rebaudioside A and rebaudioside Aα: physicochemical properties and in vivo metabolism.

莱鲍迪苷 A 和莱鲍迪苷 Aα 的比较研究:理化性质和体内代谢。

Kim Hye-Jin, Kang Hye-Jin, Lim Sangyi, Kim Ok Cheol, Yoon Ki-Nam, Lee Junhyeong, Matienzo Merc Emil, Park Min-Jung, Park Bu-Soo, Cho Jeong-Yong, Hong Seong-Jin, Kim Dong-Il, Kim Young-Min

Arid1a deficiency sensitises pancreatic cancer to fatty acid synthase inhibition.

Arid1a 缺乏症使胰腺癌对脂肪酸合成酶抑制剂更加敏感

Kuo Tzu-Lei, Hou Ya-Chin, Shan Yan-Shen, Chen Li-Tzong, Hung Wen-Chun

Preventive role of Pastinaca sativa in mitigating metabolic dysfunction-associated steatotic liver disease via modulation of metabolic endotoxemia

Pastinaca sativa 通过调节代谢性内毒血症在减轻代谢功能障碍相关脂肪肝中发挥预防作用

Ji-Eun Park, Hye-Bin Lee, Yu Ra Lee, Guijae Yoo, Hee-Kyoung Son, Sang Yoon Choi, Miri Park, Ho-Young Park
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