Anti-LAMP1 antibody - Lysosome Marker (Ab24170)
CD107a, Lysosome-associated membrane glycoprotein 1, LAMP-1, Lysosome-associated membrane protein 1, CD107 antigen-like family member A, LAMP1
详细信息
背景信息
Anti-LAMP1 antibody - Lysosome Marker (ab24170) is a rabbit polyclonal antibody and is validated for use in IHC-P, WB. Anti-LAMP1 antibody - Lysosome Marker (ab24170) has been cited over 760 times in peer reviewed journals and is trusted by the scientific community. Abcam's high quality validation processes ensure Anti-LAMP1 antibody - Lysosome Marker (ab24170) has high sensitivity and specificity. Anti-LAMP1 antibody - Lysosome Marker (ab24170) has 98 independent reviews from customers. Anti-LAMP1 antibody - Lysosome Membrane Marker (ab24170) specifically detects LAMP1 (UniProt ID: P11279; Molecular weight: 42kDa) and is sold in 100 µg selling sizes. LAMP1 (Lysosomal Associated Membrane Protein 1) is a protein that plays a crucial role in the lysosomal membrane's stability and function. It is widely used as a lysosome membrane marker in various cell types. LAMP1 is involved in processes such as autophagy and cellular homeostasis. Dysregulation of LAMP1 has been linked to several diseases, including cancer, where it may contribute to tumor cell metastasis, and neurodegenerative disorders like Parkinson's disease.
文献引用 (885)
Lymph node environment drives FSP1 targetability in metastasizing melanoma.
淋巴结环境驱动转移性黑色素瘤中 FSP1 的靶向性。
Deletion of SPI1 in microglia exacerbates amyloid pathology by impairing microglial response in Alzheimer's disease models.
在阿尔茨海默病模型中，小胶质细胞中 SPI1 的缺失会损害小胶质细胞的反应，从而加剧淀粉样蛋白病理。
Proteotoxic stress triggers TFEB- and TFE3-mediated autophagy and lysosomal biogenesis via non-canonical MTORC1 inactivation.
蛋白毒性应激通过非经典的 MTORC1 失活触发 TFEB 和 TFE3 介导的自噬和溶酶体生物合成。
Metabolites released from apoptotic cells in central nervous system orchestrates the pathological process of Alzheimer disease through improving autophagy.
中枢神经系统凋亡细胞释放的代谢物通过改善自噬作用来调控阿尔茨海默病的病理过程。
AXL Promotes Ischemic Myelin Repair Through Alleviating Myelin Debris Deposition and Lipid Droplets Accumulation.
AXL 通过减轻髓鞘碎片沉积和脂滴积累来促进缺血性髓鞘修复。
TFEB coordinates autophagosome biogenesis and ribophagy during starvation via SQSTM1.
TFEB 通过 SQSTM1 在饥饿期间协调自噬体生物合成和核糖体自噬。
LNP-Mediated CF10 Delivery Selectively Enhances Potency to Colorectal Cancer Cells and Preserves the TS/Top1 Dual Targeting Mechanism.
LNP介导的CF10递送选择性地增强了对结直肠癌细胞的效力，并保留了TS/Top1双重靶向机制。
Nitrogen cavitation enables rapid and high-yield preparation of functional cell-membrane-derived vesicles.
氮气空化技术能够快速、高产地制备功能性细胞膜衍生囊泡。
Multi-omic analysis of guided and unguided forebrain organoids reveals differences in cellular composition and metabolic profiles.
对引导式和非引导式前脑类器官的多组学分析揭示了细胞组成和代谢特征的差异。
CK1δ-dependent SNAPIN dysregulation drives lysosomal failure in HIV-1 Vpr-exposed neurons: A targetable mechanism in HAND.
CK1δ依赖的SNAPIN失调导致HIV-1 Vpr暴露神经元中的溶酶体功能障碍：HAND的一个可靶向机制。
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