Anti-Integrin beta 1 antibody [P5D2] (Ab24693)

CD29, FNRB, MDF2, MSK12, ITGB1, Integrin beta-1, Fibronectin receptor subunit beta, Glycoprotein IIa, VLA-4 subunit beta, GPIIA

反应种属:Human
抗原名称:ITGB1
应用:FCM, IF/ICC

详细信息

免疫原The exact immunogen used to generate this antibody is proprietary information.
宿主/亚型Mouse / IgG1
抗体类型Monoclonal
产品形式Liquid
纯化方式Affinity purification
储存缓冲液pH: 7.4 Preservative: 0.02% Sodium azide Constituents: PBS, 6.97% L-Arginine
储存条件运输条件: Blue Ice 推荐的短期储存条件: +4°C 推荐的长期储存条件: -20°C 储存信息: Avoid freeze / thaw cycle
无载体蛋白No

背景信息

This monoclonal antibody to integrin beta 1 has been knockout validated in ICC/IF and flow cytometry. The expected signal was observed in wild type cells and no signal was seen in knockout cells. This antibody inhibits the function of beta 1 integrins and can be used to block cell adhesion (Dittell et al., 1993 and Yokosaki et al., 1994). Product Specifications Anti-Integrin beta 1 antibody [P5D2] (ab24693) is a mouse monoclonal antibody and is validated for use in Flow Cyt, ICC/IF in human samples. Anti-Integrin beta 1 antibody [P5D2] (ab24693) specifically detects Integrin beta 1 (UniProt ID: P05556; Molecular weight: 86kDa) and is sold in 100 µg selling sizes. Quality and Validation Abcam's high quality validation processes ensure Anti-Integrin beta 1 antibody [P5D2] (ab24693) has high sensitivity and specificity. The specificity of Anti-Integrin beta 1 antibody [P5D2] (ab24693) has been confirmed by testing in knockout samples. Anti-Integrin beta 1 antibody [P5D2] (ab24693) has been cited over 90 times in peer reviewed journals and is trusted by the scientific community. Anti-Integrin beta 1 antibody [P5D2] (ab24693) has 4 independent reviews from customers. Related Products Antibody clone P5D2 is also available pre-conjugated to a variety of labels for your convenience - Alexa Fluor® 488, PE, PerCP, APC ( ab193591, ab218273, ab219738, ab221241 ). Want a custom formulation? This antibody clone is manufactured by Abcam. If you require a custom buffer formulation or conjugation for your experiments, please contact orders@abcam.com

文献引用 (89)

Organelle Sorting and Proteomic Analysis to Identify Proteins Involved in the Uptake and Intracellular Trafficking of Nanoparticles.

细胞器分选和蛋白质组学分析,以鉴定参与纳米颗粒摄取和细胞内运输的蛋白质。

Garcia Romeu Hector, Salvati Anna

Immune cells employ intermittent integrin-mediated traction forces for 3D migration.

免疫细胞利用间歇性的整合素介导的牵引力进行三维迁移。

Czerwinski Tina, Bischof Lars, Böhringer David, Kara Sibel, Strissel Pamela L, Strick Reiner, Huhn Natalie, Winterl Alexander, Gerum Richard, Wittmann Ernst, Schneider Michael, Beckmann Matthias W, Nusser Gina, Wiesinger Manuel, Budday Silvia, Lux Anja, Voskens Caroline, Fabry Ben, Mark Christoph

Decellularized extracellular matrix restores Fibronectin/Integrin β1 balance through extracellular vesicles to rejuvenate chondrocytes and alleviate osteoarthritis progression.

脱细胞细胞外基质通过细胞外囊泡恢复纤连蛋白/整合素β1平衡,从而使软骨细胞恢复活力并缓解骨关节炎的进展。

Fan Aoyuan, Pang Zhiying, Liu Zheng, Yin Feng, Wang Yiming

Influence of fluid shear stress on human limbal epithelial cells.

流体剪切应力对人角膜缘上皮细胞的影响。

Masterton Sophia, Ahearne Mark

3D hydrogel platform with macromolecular actuators for precisely controlled mechanical forces on cancer cell migration.

利用大分子致动器对癌细胞迁移施加精确控制的机械力,构建三维水凝胶平台

Li Bohan, Fu Qingyu, Lu Yan, Chen Cheng, Zhao Yingshuai, Zhao Yuanfeng, Cao Minghui, Zhou Wei, Fan Xiaoliang, Jiang Xiaoyu, Zhao Peng, Zheng Yijun

Tension-sensitive LINC-RhoA signaling prevents chromatin bridge breakage in cytokinesis.

张力敏感的LINC-RhoA信号传导可防止胞质分裂过程中染色质桥断裂。

Colonization by Porphyromonas gingivalis in cervical squamous cell carcinomas promotes metastasis through FimA/CD151/ITGB1 signaling.

牙龈卟啉单胞菌在宫颈鳞状细胞癌中的定植通过 FimA/CD151/ITGB1 信号传导促进转移。

Huang Xiuting, Zhuang Yuan, Wang Rui, Qu Jing, Tan Yuanyang, Li Liang, Pan Wenjun, Nie Huilong, Li Kefeng, Lin Yujing, Yi Liutong, Feng Xiaoyu, Lan Huimin, Wang Guangxue, Zeng Xiantao, Jiang Zhenqi, Wang De-Yun, Qiao Yongkang, Yan Yan

Mesenchymal stromal cells promote the formation of lung cancer organoids via Kindlin-2

间充质基质细胞通过 Kindlin-2 促进肺癌类器官的形成

Zhilin Sui #, Xianxian Wu #, Jiaxin Wang #, ShihJye Tan, Chao Zhao, Zhentao Yu, Chuanyue Wu, Xiaoxiao Wang, Ling Guo

TSP-1-CD47-integrin α4β1 axis drives T cell infiltration and synovial inflammation in rheumatoid arthritis

TSP-1-CD47-整合素α4β1轴驱动类风湿性关节炎中的T细胞浸润和滑膜炎症

Jialiang Hu # ,Xinmin Wang # ,Chuang Ge ,Weiyan Qi ,Zeqing Li ,Yaoyao Wang ,Wenting Lai ,Wei Ji ,Hanmei Xu

Effects of Topography and Extracellular Matrix Composition on Focal Adhesion Patterning in Human Corneal Fibroblasts.

地形和细胞外基质成分对人角膜成纤维细胞粘着斑模式的影响。

Subramanian Divya, Tjahjono Nathaniel S, Shihabeddin Tarik Z, Nammi Satweka, Miron-Mendoza Miguel, Varner Victor D, Petroll W Matthew, Schmidtke David W
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