详细信息
背景信息
This monoclonal antibody to integrin beta 1 has been knockout validated in ICC/IF and flow cytometry. The expected signal was observed in wild type cells and no signal was seen in knockout cells. This antibody inhibits the function of beta 1 integrins and can be used to block cell adhesion (Dittell et al., 1993 and Yokosaki et al., 1994). Product Specifications Anti-Integrin beta 1 antibody [P5D2] (ab24693) is a mouse monoclonal antibody and is validated for use in Flow Cyt, ICC/IF in human samples. Anti-Integrin beta 1 antibody [P5D2] (ab24693) specifically detects Integrin beta 1 (UniProt ID: P05556; Molecular weight: 86kDa) and is sold in 100 µg selling sizes. Quality and Validation Abcam's high quality validation processes ensure Anti-Integrin beta 1 antibody [P5D2] (ab24693) has high sensitivity and specificity. The specificity of Anti-Integrin beta 1 antibody [P5D2] (ab24693) has been confirmed by testing in knockout samples. Anti-Integrin beta 1 antibody [P5D2] (ab24693) has been cited over 90 times in peer reviewed journals and is trusted by the scientific community. Anti-Integrin beta 1 antibody [P5D2] (ab24693) has 4 independent reviews from customers. Related Products Antibody clone P5D2 is also available pre-conjugated to a variety of labels for your convenience - Alexa Fluor® 488, PE, PerCP, APC ( ab193591, ab218273, ab219738, ab221241 ). Want a custom formulation? This antibody clone is manufactured by Abcam. If you require a custom buffer formulation or conjugation for your experiments, please contact orders@abcam.com
文献引用 (89)
Organelle Sorting and Proteomic Analysis to Identify Proteins Involved in the Uptake and Intracellular Trafficking of Nanoparticles.
细胞器分选和蛋白质组学分析,以鉴定参与纳米颗粒摄取和细胞内运输的蛋白质。
Immune cells employ intermittent integrin-mediated traction forces for 3D migration.
免疫细胞利用间歇性的整合素介导的牵引力进行三维迁移。
Decellularized extracellular matrix restores Fibronectin/Integrin β1 balance through extracellular vesicles to rejuvenate chondrocytes and alleviate osteoarthritis progression.
脱细胞细胞外基质通过细胞外囊泡恢复纤连蛋白/整合素β1平衡,从而使软骨细胞恢复活力并缓解骨关节炎的进展。
Influence of fluid shear stress on human limbal epithelial cells.
流体剪切应力对人角膜缘上皮细胞的影响。
3D hydrogel platform with macromolecular actuators for precisely controlled mechanical forces on cancer cell migration.
利用大分子致动器对癌细胞迁移施加精确控制的机械力,构建三维水凝胶平台
Tension-sensitive LINC-RhoA signaling prevents chromatin bridge breakage in cytokinesis.
张力敏感的LINC-RhoA信号传导可防止胞质分裂过程中染色质桥断裂。
Colonization by Porphyromonas gingivalis in cervical squamous cell carcinomas promotes metastasis through FimA/CD151/ITGB1 signaling.
牙龈卟啉单胞菌在宫颈鳞状细胞癌中的定植通过 FimA/CD151/ITGB1 信号传导促进转移。
Mesenchymal stromal cells promote the formation of lung cancer organoids via Kindlin-2
间充质基质细胞通过 Kindlin-2 促进肺癌类器官的形成
TSP-1-CD47-integrin α4β1 axis drives T cell infiltration and synovial inflammation in rheumatoid arthritis
TSP-1-CD47-整合素α4β1轴驱动类风湿性关节炎中的T细胞浸润和滑膜炎症
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