Anti-Beclin 1 antibody [EPR19662] (Ab207612)

GT197, BECN1, Beclin-1, Coiled-coil myosin-like BCL2-interacting protein, Protein GT197

反应种属:Human, Mouse, Rat
抗原名称:BECN1
应用:WB, IP

详细信息

免疫原The exact immunogen used to generate this antibody is proprietary information.
宿主/亚型Rabbit / IgG
抗体类型Monoclonal
产品形式Liquid
纯化方式Affinity purification Protein A
储存缓冲液pH: 7.2 - 7.4 Preservative: 0.01% Sodium azide Constituents: PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA
储存条件运输条件: Conditional Ambient 推荐的短期储存时间: 1-2 weeks 推荐的短期储存条件: +4°C 推荐的长期储存条件: -20°C 储存信息: Avoid freeze / thaw cycle
无载体蛋白No

背景信息

What is this antibody validated in? Anti-Beclin 1 antibody [EPR19662] (ab207612) is a rabbit recombinant monoclonal antibody and is validated for use in Western Blot (WB), Immunoprecipitation (IP) in Human, Mouse, Rat samples. What is the molecular weight of Beclin 1? Anti-Beclin 1 [EPR19662] (ab207612) specifically detects a band for Beclin 1 (UniProt: Q14457) at a molecular weight of 52kDa. Trusted by the scientific community Anti-Beclin 1 [EPR19662] (ab207612) was first used in a scientific publication in 2016 and has been cited over 270 times in peer-reviewed journals. Reviewed by scientists Anti-Beclin 1 [EPR19662] (ab207612) has over 10 independent reviews from customers. Specificity confirmed The specificity of Anti-Beclin 1 antibody [EPR19662] (ab207612) has been confirmed by Western blot testing in BECN1 Knockout HeLa cells. Other related products We have a range of other formats of antibody clone [EPR19662] also available for your convenience: ab207612, Carrier free - ab227107, ab289864, Carrier free - ab289873, ab302669, Carrier free - ab302670 Patented technology Our RabMAb ® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb ® patents. What are the advantages of a recombinant monoclonal antibody? This product is a recombinant monoclonal antibody, which offers several advantages including - High batch-to-batch consistency and reproducibility - Improved sensitivity and specificity - Long-term security of supply - Animal-free batch production For more information, read more on recombinant antibodies. Trial sizes available! Test your antibody or perform pre-screening before committing to a larger quantity. Sold in 20µl. Discover our selection of trial-size antibodies.

文献引用 (402)

Microtubule affinity-regulating kinase 4 exacerbates diabetic cardiomyopathy by inhibiting UNC-51-like kinase 1-mediated mitochondrial autophagy.

微管亲和力调节激酶 4 通过抑制 UNC-51 样激酶 1 介导的线粒体自噬来加剧糖尿病心肌病。

Wu Yi, Wang Wei-Yi, Zhang Jing-Qi, Wang Sai, Zeng Zhi, Fu Lu, Li Bin

RhoA accelerates atherosclerosis progression by interacting with Hspa5.

RhoA 通过与 Hspa5 相互作用加速动脉粥样硬化的进展。

Dong Ruoyu, Cao Can, Li Jikuan, Jiang Guangwei, Tian Yunjie, Shi Xiaoming

Silencing C-X-C motif chemokine receptor inhibited autophagy of hippocampal neurons in epileptic mice by upregulating TWIK-related K(+) Channel 1.

沉默 CXC 基序趋化因子受体通过上调 TWIK 相关 K(+) 通道 1 抑制癫痫小鼠海马神经元的自噬。

MicroRNA-451 Modulates Autophagy-Related Signaling with Relevance to Renal Fibrosis in an Accelerated Mouse Model of Diabetic Kidney Disease.

MicroRNA-451 调节自噬相关信号传导,与糖尿病肾病加速小鼠模型中的肾纤维化相关。

Obiwuma Chidera, Agbor-Baiyee Baiyee-Ndang, Ghaderzadeh Sadaf, Mohit Neal, Gambhir Kanwal K, Bobga Bradley, Fluitt Maurice B

Parthenolide attenuated the endometriosis-like lesions by activating autophagy and suppressing NLRP3 inflammasome activity.

小白菊内酯通过激活自噬和抑制 NLRP3 炎症小体活性来减轻子宫内膜异位症样病变。

Jin Luhongyuan, Fu Tingting, Chi Chi, Zhou Jiayi, Lin Jun, Hou Wenjie

Expression profiling reveals coordinated dysregulation of autophagy-associated proteins in marginal zone lymphoma and therapeutic implications.

表达谱分析揭示了边缘区淋巴瘤中自噬相关蛋白的协同失调及其治疗意义。

Ruan Jingshu, Zhou Xin, Li Ai, Shan Ningning

Alterations in PD-L1 succinylation shape anti-tumor immune responses in melanoma.

PD-L1琥珀酰化改变影响黑色素瘤的抗肿瘤免疫反应

Liang Long, Kuang Xinwei, He Yi, Zhu Lin, Lau Poyee, Li Xin, Luo Dingan, Gong Lan, Zhou Wenbin, Zhang Fanglin, Liang Xiaowei, Li Zhuofeng, Hu Bin, Liu Dandan, Ding Tao, Li Hui, Zhao Shuang, Su Juan, Hung Mien-Chie, Liu Jing, Liu Hong, Chen Xiang

Macrophage TRIM21 knockout inhibits septic acute lung injury by downregulating autophagy regulator protein ubiquitination.

巨噬细胞 TRIM21 敲除通过下调自噬调节蛋白泛素化抑制脓毒症急性肺损伤。

Ginsenoside Rg1 ameliorates stress-exacerbated Parkinson's disease in mice by eliminating RTP801 and α-synuclein autophagic degradation obstacle.

人参皂苷 Rg1 通过消除 RTP801 和 α-突触核蛋白自噬降解障碍,改善小鼠因压力加剧的帕金森病

Wang Sha-Sha, Peng Ye, Fan Ping-Long, Ye Jun-Rui, Ma Wen-Yu, Wu Qing-Lin, Wang Hong-Yun, Tian Ya-Juan, He Wen-Bin, Yan Xu, Zhang Zhao, Chu Shi-Feng, Chen Nai-Hong

CLN7 protein functions at the interface between endolysosomes and stress granules to promote cell survival

CLN7蛋白在内溶酶体和应激颗粒的界面发挥作用,促进细胞存活。

Aseel Sharaireh #,Marta Guevara-Ferrer #,Anna M Ludlaim,Jonathan D Humphries,Alexander M Phillips,Andrew W Dowsey,Zehan Zhang,John R Counsell,Richard D Unwin,Sara E Mole,Ahad A Rahim,Tristan R McKay
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