Anti-SQSTM1 / p62 antibody [EPR18351] - Autophagosome Marker (Ab207305)
ORCA, OSIL, SQSTM1, Sequestosome-1, EBI3-associated protein of 60 kDa, Phosphotyrosine-independent ligand for the Lck SH2 domain of 62 kDa, Ubiquitin-binding protein p62, EBIAP, p60, p62
用户验证的应用
推荐稀释比例
- IHC-P1/2000 Perform heat-mediated antigen retrieval with Tris/EDTA buffer pH 9.0 before commencing with IHC staining protocol.
- WB1/1000
- ICC/IF1 µg/mL
- Flow Cyt (Intra)1/100 ab172730 - Rabbit monoclonal IgG, is suitable for use as an isotype control with this antibody.
- IP1/40
详细信息
背景信息
What is this antibody validated in? Anti-SQSTM1 / p62 antibody [EPR18351] (ab207305) is a rabbit recombinant monoclonal antibody and is validated for use in Western Blot (WB), Flow Cytometry (Intra), Immunoprecipitation (IP), Immunohistochemistry (IHC-P), Immunocytochemistry/immunofluorescence (ICC/IF) in Human samples. What is the molecular weight of SQSTM1 / p62? Anti-SQSTM1 / p62 [EPR18351] (ab207305) specifically detects a band for SQSTM1 / p62 (UniProt: Q13501) at a molecular weight of 47kDa. Trusted by the scientific community Anti-SQSTM1 / p62 [EPR18351] (ab207305) was first used in a scientific publication in 2016 and has been cited over 40 times in peer-reviewed journals. Specificity confirmed The specificity of Anti-SQSTM1 / p62 antibody [EPR18351] (ab207305) has been confirmed by Western blot testing in SQSTM1 Knockout HAP1 cells. Patented technology Our RabMAb ® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb ® patents. What are the advantages of a recombinant monoclonal antibody? This product is a recombinant monoclonal antibody, which offers several advantages including - High batch-to-batch consistency and reproducibility - Improved sensitivity and specificity - Long-term security of supply - Animal-free batch production For more information, read more on recombinant antibodies. Trial sizes available! Test your antibody or perform pre-screening before committing to a larger quantity. Sold in 20µl. Discover our selection of trial-size antibodies.
文献引用 (100)
Lactate-driven ATP6V1B2 lactylation triggers asthmatic inflammation by linking lysosomal dysfunction to mitochondrial ROS-dependent pyroptosis.
乳酸驱动的 ATP6V1B2 乳酸化通过将溶酶体功能障碍与线粒体 ROS 依赖性细胞焦亡联系起来，从而引发哮喘炎症。
Formyl Peptide Receptor-2-Suppressed Autophagy Promotes the Migration and Invasion of Human Glioblastoma Cells Through PI3K/Akt Signaling.
甲酰肽受体-2抑制自噬通过PI3K/Akt信号通路促进人类胶质母细胞瘤细胞的迁移和侵袭。
HOXA7 Impairs Osteogenic Differentiation via p38/JNK Signaling: Implications for Osteoporosis.
HOXA7 通过 p38/JNK 信号通路抑制成骨分化：对骨质疏松症的影响。
Hyaluronic acid-tailored prodrug nanoplatforms for efficiently overcoming colorectal cancer chemoresistance and recurrence by synergistic inhibition of cancer cell stemness.
利用透明质酸定制的前药纳米平台，通过协同抑制癌细胞干性，有效克服结直肠癌的化疗耐药性和复发
Neodymium-doped mesoporous silica nanoparticles promote bone regeneration via autophagy-mediated macrophage immunomodulation.
钕掺杂介孔二氧化硅纳米颗粒通过自噬介导的巨噬细胞免疫调节促进骨再生
α-hederin Targets USP5 to Inhibit Colorectal Tumorigenesis by Disrupting STAT3 Deubiquitination.
α-常春藤碱靶向 USP5，通过破坏 STAT3 去泛素化来抑制结直肠肿瘤发生。
High glucose levels promote glycolysis and cholesterol synthesis via ERRα and suppress the autophagy-lysosomal pathway in endometrial cancer.
高葡萄糖水平通过 ERRα 促进糖酵解和胆固醇合成，并抑制子宫内膜癌中的自噬-溶酶体途径
TRAP1 inhibits KANSL3 acetylation to alleviate mitochondrial dysfunction by promoting mitophagy in cardiomyocytes under diabetic conditions.
TRAP1抑制KANSL3乙酰化，通过促进糖尿病条件下心肌细胞的线粒体自噬来缓解线粒体功能障碍。
ATP5F1A deficiency causes developmental delay and motor dysfunction in humans and zebrafish.
ATP5F1A 缺乏会导致人类和斑马鱼发育迟缓和运动功能障碍
Targeting ESR1 restores SQSTM1-dependent autophagy and sensitizes ER-positive breast cancer to oxidative and radiation stress.
靶向 ESR1 可恢复 SQSTM1 依赖性自噬，并使 ER 阳性乳腺癌对氧化应激和辐射应激更加敏感。
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