Anti-GSDMD antibody [EPR19829] (Ab210070)
DFNA5L, GSDMDC1, FKSG10, GSDMD, Gasdermin-D, Gasdermin domain-containing protein 1
用户验证的应用
推荐稀释比例
- WB1/1000
详细信息
背景信息
Anti-GSDMD antibody [EPR19829] (ab210070) was developed by Abcam using patented rabbit monoclonal antibody technology and is validated for use in WB in human samples. Anti-GSDMD antibody [EPR19829] (ab210070) has been cited over 57 times in peer reviewed journals and is trusted by the scientific community. Abcams high quality manufacturing and validation processes ensure Anti-GSDMD antibody [EPR19829] (ab210070) has high sensitivity and specificity alongside high lot-to-lot consistency and reproducibility. The specificity of Anti-GSDMD antibody [EPR19829] (ab210070) has been confirmed by testing in knockout samples. Anti-GSDMD antibody [EPR19829] (ab210070) specifically detects GSDMD (UniProt ID: P57764; Molecular weight: 53kDa) and is sold in 100 uL and 1 mL selling sizes. Conjugation-ready, carrier free format available for antibody clone EPR19829 - ab232485. GSDMD is crucial for mediating pyroptosis, a form of programmed cell death, and plays a significant role in inflammatory responses and immune defense against infections What are the advantages of a recombinant monoclonal antibody? This product is a recombinant monoclonal antibody, which offers several advantages including - High batch-to-batch consistency and reproducibility - Improved sensitivity and specificity - Long-term security of supply - Animal-free batch production For more information, read more on recombinant antibodies.
文献引用 (121)
Aptamer-functionalized exosomes combined with doxorubicin suppress GBM progression and enhance chemoradiosensitivity by promoting pyroptosis.
适体功能化的外泌体与阿霉素联合使用,通过促进细胞焦亡抑制胶质母细胞瘤进展并增强化疗和放射敏感性。
Targeted Induction of Cancer Cell Necroptosis Potentiates Anti-PD-1 Immunotherapy via CD80 Activation.
靶向诱导癌细胞坏死性凋亡通过 CD80 激活增强抗 PD-1 免疫疗法。
The NLRP6 inflammasome is activated by sterile or pathogen-induced endolysosomal damage
NLRP6炎症小体可被无菌性或病原体诱导的内溶酶体损伤激活。
Redefining Shiga toxin-induced human cell death as NLRP1- and gasdermin E-mediated pyroptosis.
将志贺毒素诱导的人类细胞死亡重新定义为 NLRP1 和 gasdermin E 介导的细胞焦亡。
An atom-edged magnetic nanomotor for cancer mechanotherapy.
用于癌症机械疗法的原子级磁性纳米马达。
HMGN2 induces pyroptosis in tumour cells by modulating the STT3B/PDâL1/caspaseâ1/GSDMD axis.
HMGN2 通过调节 STT3B/PD-L1/caspase-1/GSDMD 轴诱导肿瘤细胞焦亡。
CTSB mediates oxidative stress and intestinal epithelial barrier disruption in intestinal ischemiaâreperfusion injury.
CTSB介导肠缺血再灌注损伤中的氧化应激和肠上皮屏障破坏。
Activation of TRPV4 to drive pyroptosis-dependent orthodontic tooth remodeling.
激活 TRPV4 以驱动依赖于细胞焦亡的正畸牙齿重塑。
Aurora kinase B phosphorylates ZBP1 to drive PANoptosis following treatment with PARP and ATR inhibitors combination.
Aurora 激酶 B 磷酸化 ZBP1,在 PARP 和 ATR 抑制剂联合治疗后驱动 PANoptosis。
RING1 dictates GSDMD-mediated inflammatory response and host susceptibility to pathogen infection.
RING1 决定 GSDMD 介导的炎症反应和宿主对病原体感染的易感性。
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