Anti-LAMP1 antibody [EPR21026] - Lysosome Marker (Ab208943)

特异性

In our lab we observe staining in multiple tissues (spleen, lung, kidney etc.) in IHC-P with ab208943, but a lack of staining on mouse brain. We have received feedback from other researchers, that they also do not see staining in mouse brain with this antibody. Therefore we do not recommend using this reagent, for work on mouse brain, in IHC-P. For further information on this please contact our Technical Support team who will be happy to help.

Anti-LAMP1 antibody [EPR21026] (ab208943) was developed by Abcam using patented rabbit monoclonal antibody technology and is validated for use in Flow Cyt (Intra), ICC/IF, IHC-Fr, IHC-P, IP, WB in mouse samples. Anti-LAMP1 antibody [EPR21026] (ab208943) has been cited over 31 times in peer reviewed journals and is trusted by the scientific community. Abcams high quality manufacturing and validation processes ensure Anti-LAMP1 antibody [EPR21026] (ab208943) has high sensitivity and specificity alongside high lot-to-lot consistency and reproducibility. Anti-LAMP1 antibody [EPR21026] (ab208943) specifically detects LAMP1 (UniProt ID: P11438; Molecular weight: 42kDa) and is sold in 100 uL and 1 mL selling sizes. Conjugation-ready, carrier free format available for antibody clone EPR21026 - ab225762. Antibody clone EPR21026 is also available pre-conjugated to a variety of labels for your convenience - Alexa Fluor® 647, Alexa Fluor® 555, Alexa Fluor® 594, Alexa Fluor® 568, PE (ab23737, ab355, ab32684, ab3282, ab314256 ). Lysosomal-associated membrane protein 1 (LAMP1) is an essential lysosomal membrane protein that plays a crucial role in cellular processes such as waste degradation and autophagy regulation. It is a significant focus of research in neuroscience and cell biology due to its importance in maintaining cellular health. Changes in LAMP1 expression are associated with various diseases, including cancer, neurodegenerative disorders like Alzheimer's disease (AD), and lysosomal storage diseases. Studying LAMP1 provides valuable insights into the mechanisms of these diseases and the cellular dysfunctions involved, highlighting its critical role in understanding disease pathology. Patented technology Our RabMAb ® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb ® patents. What are the advantages of a recombinant monoclonal antibody? This product is a recombinant monoclonal antibody, which offers several advantages including - High batch-to-batch consistency and reproducibility - Improved sensitivity and specificity - Long-term security of supply - Animal-free batch production For more information, read more on recombinant antibodies.