Anti-Lamin A antibody - Nuclear Envelope Marker (Ab26300)

LMN1, LMNA, Prelamin-A/C

反应种属:Human, Mouse, Rat
抗原名称:LMNA
应用:WB, IF/ICC

详细信息

免疫原The exact immunogen used to generate this antibody is proprietary information.
宿主/亚型Rabbit / IgG
抗体类型Polyclonal
产品形式Liquid
纯化方式Affinity purification Immunogen
储存缓冲液pH: 7.4 Preservative: 0.02% Sodium azide Constituents: PBS, 1% BSA
储存条件运输条件: Blue Ice 推荐的短期储存时间: 1-2 weeks 推荐的短期储存条件: +4°C 推荐的长期储存条件: -20°C 储存信息: Avoid freeze / thaw cycle

特异性

Replenishment batches of ab26300 are tested in WB. Previous batches were additionally validated in ICC/IF. This application is still expected to work and is covered by our Abpromise guarantee.

背景信息

What is this antibody validated in? Anti-Lamin A antibody (ab26300) is a rabbit polyclonal antibody and is validated for use in Western Blot (WB), Immunocytochemistry/immunofluorescence (ICC/IF) in Human, Mouse, Rat samples. What is the molecular weight of Lamin A? Anti-Lamin A (ab26300) specifically detects a band for Lamin A (UniProt: P02545) at a molecular weight of 74kDa. Trusted by the scientific community Anti-Lamin A (ab26300) was first used in a scientific publication in 2006 and has been cited over 110 times in peer-reviewed journals. Reviewed by scientists Anti-Lamin A (ab26300) has over 20 independent reviews from customers. Specificity confirmed The specificity of Anti-Lamin A antibody (ab26300) has been confirmed by Western blot testing in LMNA Knockout HAP1 cell line, ab261787.

文献引用 (128)

Interphase chromosome conformation is specified by distinct folding programmes inherited through mitotic chromosomes or the cytoplasm.

间期染色体构象是由通过有丝分裂染色体或细胞质遗传的不同折叠程序决定的。

Schooley Allana, Venev Sergey V, Aksenova Vasilisa, Lehman Jesse W, Navarrete Emily, Pai Athma A, Dasso Mary, Dekker Job

Nucleus softens during herpesvirus infection.

疱疹病毒感染期间细胞核会软化。

Tervonen Aapo, Ruokolainen Visa, Leclerc Simon, Tieu Katie, Lyonnais Sébastien, Niskanen Henri, Chen Jian-Hua, Gupta Alka, Kaikkonen Minna U, Larabell Carolyn A, Muriaux Delphine, Mattola Salla, Conway Daniel E, Ihalainen Teemu O, Aho Vesa, Vihinen-Ranta Maija

Protocol for analyzing the microstructure of nuclear fiber layers by using structured illumination microscopy coupled with Arivis 4D.

利用结构光照明显微镜结合 Arivis 4D 分析核纤维层微观结构的方案。

Guan Miao, Li Kewei, Liu Xianglong, Li Xiaoliang, Sun Zhenlong

STING causes replication stress and nascent DNA degradation via SAMHD1.

STING 通过 SAMHD1 引起复制压力和新生 DNA 降解。

Teodoro-Castro Barbara, de Faria Rafael Cancado, Shashkova Elena V, Malique Atika, Adolph Madison B, Silva Lilian N D, Gonzalo Susana

DNA double-stranded breaks, a hallmark of aging, defined at the nucleotide resolution, are increased and associated with transcription in the cardiac myocytes in LMNA-cardiomyopathy.

DNA双链断裂是衰老的标志,其在核苷酸分辨率下定义,在LMNA心肌病中,心肌细胞中的DNA双链断裂增加,并与转录相关。

Cathcart Benjamin, Cheedipudi Sirisha M, Rouhi Leila, Zhao Zhongming, Gurha Priyatansh, Marian Ali J

The molecular basis of lamin-specific chromatin interactions.

层粘蛋白特异性染色质相互作用的分子基础。

Wang Baihui, Kronenberg-Tenga Rafael, Rosti Valentina, Di Patrizio Soldateschi Emanuele, Luo Qiang, Iannacchero Ugo Maria, Pinet Louise, Eibauer Matthias, Boujemaa-Paterski Rajaa, Schuler Benjamin, Lanzuolo Chiara, Medalia Ohad

RNA-binding proteins hnRNPM and ELAVL1 promote type-I interferon induction downstream of the nucleic acid sensors cGAS and RIG-I

RNA 结合蛋白 hnRNPM 和 ELAVL1 促进核酸传感器 cGAS 和 RIG-I 下游的 I 型干扰素诱导

Alexander Kirchhoff, Anna-Maria Herzner, Christian Urban, Antonio Piras, Robert Düster, Julia Mahlberg, Agathe Grünewald, Thais M Schlee-Guimarães, Katrin Ciupka, Petro Leka, Robert J Bootz, Christina Wallerath, Charlotte Hunkler, Ann Kristin de Regt, Beate M Kümmerer, Maria Hønholt Christensen, Flo

Acute chromatin decompaction stiffens the nucleus as revealed by nanopillar-induced nuclear deformation in cells.

急性染色质解压缩会使细胞核变硬,这可以通过纳米柱诱导的细胞核变形来揭示

Mitra Aninda, Cutiongco Marie F A, Burla Romina, Zeng Yongpeng, Na Qin, Kong Mengya, Vinod Benjamin, Nai Mui Hoon, Hübner Barbara, Ludwig Alexander, Lim Chwee Teck, Shivashankar G V, Saggio Isabella, Zhao Wenting

Tension-sensitive LINC-RhoA signaling prevents chromatin bridge breakage in cytokinesis.

张力敏感的LINC-RhoA信号传导可防止胞质分裂过程中染色质桥断裂。

Lack of myotubularin phosphatase activity is the main cause of X-linked myotubular myopathy.

肌管蛋白磷酸酶活性缺乏是X连锁肌管性肌病的主要原因。

Moschovaki-Filippidou Foteini, Kretz Christine, Reiss David, Chicanne Gaëtan, Payrastre Bernard, Laporte Jocelyn
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