Anti-RNA polymerase II CTD repeat YSPTSPS antibody - ChIP Grade (Ab26721)
POLR2, POLR2A, DNA-directed RNA polymerase II subunit RPB1, RNA polymerase II subunit B1, 3'-5' exoribonuclease, DNA-directed RNA polymerase II subunit A, DNA-directed RNA polymerase III largest subunit, RNA-directed RNA polymerase II subunit RPB1
详细信息
特异性
Replenishment batches of our polyclonal antibody, ab26721 are tested in ChIP. Previous batches were additionally validated in ICC/IF, IHC-P, IP and WB. These applications are still expected to work and are covered by our Abpromise guarantee. You may also be interested in our alternative recombinant antibody, ab238146.
背景信息
Anti-RNA polymerase II CTD repeat YSPTSPS antibody - ChIP Grade (ab26721) is a rabbit polyclonal antibody and is validated for use in ChIP, ICC/IF, IHC-P, IP, WB in arabidopsis thaliana, caenorhabditis elegans, drosophila melanogaster, human, mouse, rat, saccharomyces cerevisiae, schizosaccharomyces pombe, xenopus laevis, zebrafish samples. Anti-RNA polymerase II CTD repeat YSPTSPS antibody - ChIP Grade (ab26721) has been cited over 55 times in peer reviewed journals and is trusted by the scientific community. Abcam's high quality validation processes ensure Anti-RNA polymerase II CTD repeat YSPTSPS antibody - ChIP Grade (ab26721) has high sensitivity and specificity. Anti-RNA polymerase II CTD repeat YSPTSPS antibody - ChIP Grade (ab26721) has 8 independent reviews from customers. Anti-RNA polymerase II CTD repeat YSPTSPS antibody - ChIP Grade (ab26721) specifically detects RNA polymerase II CTD repeat YSPTSPS (UniProt ID: P24928; Molecular weight: 217kDa) and is sold in 100 µg selling sizes. RNA polymerase II CTD repeat YSPTSPS is essential for transcription regulation and gene expression. Utilizing our highly specific RNA polymerase II CTD repeat YSPTSPS antibody can significantly enhance the detection and study of this modification. Research indicates that phosphorylation of the CTD repeat YSPTSPS is crucial for the transition from transcription initiation to elongation, impacting various cellular processes and disease states. Phosphorylation of RNA polymerase II at the CTD repeat YSPTSPS is critical for proper mRNA synthesis and processing. Abnormal phosphorylation patterns are linked to transcriptional dysregulation in cancer, pediatric gliomas, chondroblastomas, and neurodevelopmental syndromes. Studying these modifications can provide insights into potential therapeutic targets for various conditions.
文献引用 (85)
Precise control of transcription condensates across S phase balances linker histone expression with DNA replication, ensuring genome stability.
S 期转录凝聚体的精确控制平衡了连接组蛋白的表达和 DNA 复制，从而确保基因组的稳定性。
Site-specific phosphorylation of LRP regulates FLC chromatin looping and flowering.
LRP 的位点特异性磷酸化调节 FLC 染色质环化和开花。
Nuclear ANLN regulates transcription initiation related Pol II clustering and target gene expression
核 ANLN 调节转录起始相关的 Pol II 聚集和靶基因表达
The Super Enhancer-Driven Long Noncoding RNA PRKCQ-AS1 Promotes Neuroblastoma Tumorigenesis by Interacting With MSI2 Protein and Is Targetable by Small Molecule Compounds.
超级增强子驱动的长链非编码RNA PRKCQ-AS1通过与MSI2蛋白相互作用促进神经母细胞瘤的发生，并且可作为小分子化合物的靶点
IncRNA-ZFAS1, an Emerging Gate-Keeper in DNA Damage-Dependent Transcriptional Regulation.
IncRNA-ZFAS1，DNA损伤依赖性转录调控中的新兴守门人
Molecular recognition and effects of a benzothiazole derivative targeting the MYC G-quadruplex.
苯并噻唑衍生物靶向 MYC G-四链体的分子识别和效应。
SLFN14 functions as a P-TEFb inhibitor to modulate the transcription of HIV-1 and cellular genes
SLFN14 作为 P-TEFb 抑制剂，可调节 HIV-1 和细胞基因的转录。
Combined inhibition of KAT6A/B and Menin reverses estrogen receptor-driven gene expression programs in breast cancer
联合抑制KAT6A/B和Menin可逆转乳腺癌中雌激素受体驱动的基因表达程序
IT-scC&T-seq streamlines scalable, parallel profiling of protein-DNA interactions in single cells.
IT-scC&T-seq 简化了单细胞中蛋白质-DNA相互作用的可扩展并行分析
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