Anti-FOXP3 antibody [EPR22102-37] (Ab215206)

IPEX, JM2, FOXP3, Forkhead box protein P3, Scurfin

反应种属:Human, Mouse, Rat
抗原名称:FOXP3
应用:WB, FCM, IP

详细信息

免疫原The exact immunogen used to generate this antibody is proprietary information.
宿主/亚型Rabbit / IgG
抗体类型Monoclonal
产品形式Liquid
纯化方式Affinity purification Protein A
储存缓冲液pH: 7.2 - 7.4 Preservative: 0.01% Sodium azide Constituents: PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA
储存条件运输条件: Conditional Ambient 推荐的短期储存时间: 1-2 weeks 推荐的短期储存条件: +4°C 推荐的长期储存条件: -20°C 储存信息: Avoid freeze / thaw cycle
无载体蛋白No

特异性

We do not guarantee WB for rat. According to our preliminary WB data, this antibody failed to detect endogenous expression of FOXP3 in the tissues tested in WB, such as thymus. It might work in CD4+CD25+ Treg cells with abundant FOXP3, but we don't have experimental data to support that.

背景信息

Anti-FOXP3 antibody [EPR22102-37] (ab215206) was developed by Abcam using patented rabbit monoclonal antibody technology and is validated for use in Flow Cyt (Intra), IP, WB in human, mouse, rat samples. Anti-FOXP3 antibody [EPR22102-37] (ab215206) has been cited over 67 times in peer reviewed journals and is trusted by the scientific community. Abcams high quality manufacturing and validation processes ensure Anti-FOXP3 antibody [EPR22102-37] (ab215206) has high sensitivity and specificity alongside high lot-to-lot consistency and reproducibility. Anti-FOXP3 antibody [EPR22102-37] (ab215206) has 5 independent reviews from customers. Anti-FOXP3 antibody [EPR22102-37] (ab215206) specifically detects FOXP3 (UniProt ID: Q9BZS1; Molecular weight: 47kDa) and is sold in a convenient trial size to enable initial testing (20 uL) and larger sizes for subsequent scaling up experiments (100 uL and 1 mL). Conjugation-ready, carrier free format available for antibody clone EPR22102-37 - ab244242. FOXP3 is a key transcription factor that regulates the development and function of regulatory T cells (Tregs), which help maintain immune tolerance. In oncology, high FOXP3 expression is often linked to poor prognosis as it can enable tumors to evade the immune system. This makes FOXP3 a potential biomarker for predicting the effectiveness of immunotherapy treatments. Patented technology Our RabMAb ® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb ® patents. What are the advantages of a recombinant monoclonal antibody? This product is a recombinant monoclonal antibody, which offers several advantages including - High batch-to-batch consistency and reproducibility - Improved sensitivity and specificity - Long-term security of supply - Animal-free batch production For more information, read more on recombinant antibodies.

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