Anti-TGF beta 1 antibody [EPR21143] (Ab215715)

TGFB, TGFB1, Transforming growth factor beta-1 proprotein

反应种属:Human, Mouse, Rat
抗原名称:TGFB1
应用:WB, IHC

详细信息

免疫原The exact immunogen used to generate this antibody is proprietary information.
宿主/亚型Rabbit / IgG
抗体类型Monoclonal
产品形式Liquid
纯化方式Affinity purification Protein A
储存缓冲液pH: 7.2 - 7.4 Preservative: 0.01% Sodium azide Constituents: PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA
储存条件运输条件: Conditional Ambient 推荐的短期储存时间: 1-2 weeks 推荐的短期储存条件: +4°C 推荐的长期储存条件: -20°C 储存信息: Avoid freeze / thaw cycle
无载体蛋白No

特异性

For testing samples with low expression level of TGF beta 1, we recommend ab179695 which could give stronger signal. Loading larger amount of lysate or lower antibody dilution would also help.

背景信息

Anti-TGFB1 antibody [EPR21143] (ab215715) was developed by Abcam using patented rabbit monoclonal antibody technology and is validated for use in IHC-P and WB. Anti-TGF beta 1 antibody [EPR21143] (ab215715) was first used in a scientific publication in 2019 and has been cited over 223 times in peer reviewed journals. It's performance in Western blot in human, mouse and rat samples is trusted by the scientific community. Abcam's high quality manufacturing and validation processes ensure Anti-TGF beta 1 antibody [EPR21143] (ab215715) has high sensitivity and specificity alongside high lot-to-lot consistency and reproducibility. The specificity of Anti-TGF beta 1 antibody [EPR21143] (ab215715) has been confirmed by Western Blot testing in TGF beta 1 knockout A549 cells ( ab269509 ). Anti-TGF beta 1 antibody [EPR21143] (ab215715) has 6 independent reviews from customers. Anti-TGFB1 antibody [EPR21143] (ab215715) specifically detects TGF beta 1 (UniProt ID: P04202; Molecular weight: 29kDa) and is sold in 100 µL and 1 mL selling sizes. Conjugation-ready, carrier free format available for antibody clone EPR21143 - ab229856. Antibody clone EPR21143 is also available pre-conjugated to a variety of labels for your convenience - Alexa Fluor® 647, Alexa Fluor® 488, Alexa Fluor® 555 ( ab281316, ab313729, ab313730 ). TGF-β1 (Transforming Growth Factor Beta 1) is a cytokine that suppresses immune cell activity, aiding tumor growth and immune evasion. It also regulates the tumor microenvironment, contributing to fibrosis and tissue remodeling. Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents. This product is a recombinant monoclonal antibody, which offers several advantages including - High batch-to-batch consistency and reproducibility - Improved sensitivity and specificity - Long-term security of supply - Animal-free batch production For more information, read more on recombinant antibodies. Patented technology Our RabMAb ® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb ® patents. What are the advantages of a recombinant monoclonal antibody? This product is a recombinant monoclonal antibody, which offers several advantages including - High batch-to-batch consistency and reproducibility - Improved sensitivity and specificity - Long-term security of supply - Animal-free batch production For more information, read more on recombinant antibodies.

文献引用 (534)

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ElSheikh Hager, Salvers Annika, Piesker Judith, Buchholz Shenja, Lange Rabea, Ameling Sabine, Steil Leif, Hammer Elke, Homuth Georg, Völker Uwe, Bröker Barbara M, Weiss Frank U, Sendler Matthias, Glaubitz Juliane

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癌细胞衍生的唾液酸化 IgG 与 Siglec-7/9/10 相互作用,是胰腺癌潜在的免疫治疗靶点。

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Rescue Radiosensitization of Pancreatic Cancer via PD-L1/TGF-β1 Dual-Blockade Nanotherapy as Evaluated in 3-Dimensional Microtumors.

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Secreted RCN3 acts as an early epithelial-fibroblast mediator via TGFβR1-Smad signaling in post-ALI pulmonary fibrosis.

分泌型 RCN3 通过 TGFβR1-Smad 信号传导在 ALI 后肺纤维化中发挥早期上皮成纤维细胞介质的作用。

Prophylactic quercetin administration attenuates pulmonary fibrosis via ferroptosis-resistant priming of alveolar epithelial cells.

预防性给予槲皮素可通过增强肺泡上皮细胞的抗铁死亡能力来减轻肺纤维化。

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Crosstalk of NPY and TGFβ orchestrates the signaling to facilitate perineural invasion of oral squamous cell carcinoma.

NPY 和 TGFβ 的相互作用协调信号传导,促进口腔鳞状细胞癌的神经周围侵袭。

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少免疫性毛细血管内增生性肾小球肾炎伴肾小球M2巨噬细胞浸润。

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