Anti-TGF beta 1 antibody [EPR21143] (Ab215715)
TGFB, TGFB1, Transforming growth factor beta-1 proprotein
详细信息
特异性
For testing samples with low expression level of TGF beta 1, we recommend ab179695 which could give stronger signal. Loading larger amount of lysate or lower antibody dilution would also help.
背景信息
Anti-TGFB1 antibody [EPR21143] (ab215715) was developed by Abcam using patented rabbit monoclonal antibody technology and is validated for use in IHC-P and WB. Anti-TGF beta 1 antibody [EPR21143] (ab215715) was first used in a scientific publication in 2019 and has been cited over 223 times in peer reviewed journals. It's performance in Western blot in human, mouse and rat samples is trusted by the scientific community. Abcam's high quality manufacturing and validation processes ensure Anti-TGF beta 1 antibody [EPR21143] (ab215715) has high sensitivity and specificity alongside high lot-to-lot consistency and reproducibility. The specificity of Anti-TGF beta 1 antibody [EPR21143] (ab215715) has been confirmed by Western Blot testing in TGF beta 1 knockout A549 cells ( ab269509 ). Anti-TGF beta 1 antibody [EPR21143] (ab215715) has 6 independent reviews from customers. Anti-TGFB1 antibody [EPR21143] (ab215715) specifically detects TGF beta 1 (UniProt ID: P04202; Molecular weight: 29kDa) and is sold in 100 µL and 1 mL selling sizes. Conjugation-ready, carrier free format available for antibody clone EPR21143 - ab229856. Antibody clone EPR21143 is also available pre-conjugated to a variety of labels for your convenience - Alexa Fluor® 647, Alexa Fluor® 488, Alexa Fluor® 555 ( ab281316, ab313729, ab313730 ). TGF-β1 (Transforming Growth Factor Beta 1) is a cytokine that suppresses immune cell activity, aiding tumor growth and immune evasion. It also regulates the tumor microenvironment, contributing to fibrosis and tissue remodeling. Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents. This product is a recombinant monoclonal antibody, which offers several advantages including - High batch-to-batch consistency and reproducibility - Improved sensitivity and specificity - Long-term security of supply - Animal-free batch production For more information, read more on recombinant antibodies. Patented technology Our RabMAb ® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb ® patents. What are the advantages of a recombinant monoclonal antibody? This product is a recombinant monoclonal antibody, which offers several advantages including - High batch-to-batch consistency and reproducibility - Improved sensitivity and specificity - Long-term security of supply - Animal-free batch production For more information, read more on recombinant antibodies.
文献引用 (534)
HCMV infection disrupts barrier functions and promotes epithelial-mesenchymal transition in a cholangiocyte organoid model.
HCMV 感染会破坏胆管细胞类器官模型的屏障功能,并促进上皮-间质转化。
Endometrial Assembloid Model Reveals Endometrial Gland Development Regulation by Estradiol-Driven WNT7B Suppression.
子宫内膜类动物模型揭示了雌二醇驱动的 WNT7B 抑制对子宫内膜腺体发育的调控作用。
IL-4/STAT6-signaling Influences Local Inflammation and Regeneration Processes During Acute Pancreatitis and Promotes Fibrosis by a Direct Activation of Pancreatic Fibroblasts During Chronic Pancreatitis.
IL-4/STAT6 信号传导影响急性胰腺炎期间的局部炎症和再生过程,并通过直接激活慢性胰腺炎期间的胰腺成纤维细胞促进纤维化。
Intravesical instillation of pirfenidone/polydopamine nanoparticles for managing neurogenic bladder post-spinal cord injury by alleviating bladder inflammation and fibrosis.
通过膀胱内灌注吡非尼酮/聚多巴胺纳米颗粒治疗脊髓损伤后神经源性膀胱,减轻膀胱炎症和纤维化。
Cancer cell-derived sialylated IgG interacting with Siglec-7/9/10 is a potential immunotherapeutic target in pancreatic cancer.
癌细胞衍生的唾液酸化 IgG 与 Siglec-7/9/10 相互作用,是胰腺癌潜在的免疫治疗靶点。
Rescue Radiosensitization of Pancreatic Cancer via PD-L1/TGF-β1 Dual-Blockade Nanotherapy as Evaluated in 3-Dimensional Microtumors.
通过 PD-L1/TGF-β1 双重阻断纳米疗法在三维微肿瘤中评估其对胰腺癌放射增敏作用。
Secreted RCN3 acts as an early epithelial-fibroblast mediator via TGFβR1-Smad signaling in post-ALI pulmonary fibrosis.
分泌型 RCN3 通过 TGFβR1-Smad 信号传导在 ALI 后肺纤维化中发挥早期上皮成纤维细胞介质的作用。
Prophylactic quercetin administration attenuates pulmonary fibrosis via ferroptosis-resistant priming of alveolar epithelial cells.
预防性给予槲皮素可通过增强肺泡上皮细胞的抗铁死亡能力来减轻肺纤维化。
Crosstalk of NPY and TGFβ orchestrates the signaling to facilitate perineural invasion of oral squamous cell carcinoma.
NPY 和 TGFβ 的相互作用协调信号传导,促进口腔鳞状细胞癌的神经周围侵袭。
Pauci-Immune Endocapillary Proliferative Glomerulonephritis With Glomerular M2 Macrophage Infiltration.
少免疫性毛细血管内增生性肾小球肾炎伴肾小球M2巨噬细胞浸润。
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