Anti-CD8 alpha antibody [EPR21769] (Ab217344)
CD8a, Lyt-2, Lyt2, Cd8a, T-cell surface glycoprotein CD8 alpha chain, T-cell surface glycoprotein Lyt-2
用户验证的应用
推荐稀释比例
- IHC-P1/2000 Background staining was observed in mouse testis samples. Perform heat-mediated antigen retrieval with Tris/EDTA buffer pH 9.0 before commencing with IHC staining protocol.
- WB1/1000
- Flow Cyt1/500
- IP1/30
- IHC-Fr1/500
详细信息
背景信息
Anti-CD8 alpha antibody [EPR21769] (ab217344) was developed by Abcam using patented rabbit monoclonal antibody technology and is validated for use in Flow Cyt, IHC-Fr IHC-P, IP and WB. Anti-CD8 alpha antibody [EPR21769] (ab217344) was first used in a scientific publication in 2019 and has been cited over 164 times in peer reviewed journals. It's performance in IHC and Immunofluorescence in mouse samples is trusted by the scientific community. Abcam's high quality manufacturing and validation processes ensure Anti-CD8 alpha antibody [EPR21769] (ab217344) has high sensitivity and specificity alongside high lot-to-lot consistency and reproducibility. Anti-CD8 alpha antibody [EPR21769] (ab217344) has 4 independent reviews from customers. Anti-CD8 alpha antibody [EPR21769] (ab217344) specifically detects CD8 alpha (UniProt ID: P01731; Molecular weight: 25kDa) and is sold in 100 µL and 1 mL selling sizes. Conjugation-ready, carrier free format available for antibody clone EPR21769 - ab230156. Antibody clone EPR21769 is also available pre-conjugated to a variety of labels for your convenience - Alexa Fluor ® 488, Alexa Fluor ® 647, FITC, APC, Alexa Fluor ® 594, Alexa Fluor ® 555, PE ( ab237364, ab237365, ab237367, ab237368, ab277939, ab280863, ab306536 ). CD8 alpha is involved in diseases by aiding cytotoxic T cells in targeting and eliminating infected or malignant cells. CD8 T cell dysfunction is associated with several diseases including Autoimmune disease, cancer and infectious diseases. Patented technology Our RabMAb ® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb ® patents. What are the advantages of a recombinant monoclonal antibody? This product is a recombinant monoclonal antibody, which offers several advantages including - High batch-to-batch consistency and reproducibility - Improved sensitivity and specificity - Long-term security of supply - Animal-free batch production For more information, read more on recombinant antibodies.
文献引用 (496)
A biosafe mouse model for SARS-CoV-2 infection that more realistically simulates COVID-19 symptoms.
一种生物安全的SARS-CoV-2感染小鼠模型,能够更真实地模拟COVID-19症状。
Tumour-infiltrating microplastics disrupt the JAK-STAT-microbiota axis to promote immunotherapy resistance in colorectal cancer.
肿瘤浸润性微塑料会破坏 JAK-STAT-微生物群轴,从而促进结直肠癌的免疫治疗耐药性。
Nerves Stimulate Cross-talk Between Gastric Cancer and Group 3 Innate Lymphoid Cells to Enhance Immunosuppression.
神经刺激胃癌与第 3 组固有淋巴细胞之间的相互作用,从而增强免疫抑制。
Identification of altered immune landscape at single-cell resolution in NSCLC brain metastasis and its association with poor immune checkpoint inhibitor responses.
在单细胞分辨率下识别非小细胞肺癌脑转移中改变的免疫景观及其与免疫检查点抑制剂反应不良的关系。
Combination of PARP and KRAS(G12D) inhibitors enhances therapeutic efficacy by exploiting vulnerabilities in PDAC.
PARP 和 KRAS(G12D) 抑制剂的联合应用,利用 PDAC 的弱点,增强了治疗效果。
Long-acting interleukin-7 improves the efficacy of oncolytic viral therapy in glioblastoma.
长效白细胞介素-7可提高溶瘤病毒疗法治疗胶质母细胞瘤的疗效。
Boron neutron capture therapy preserves immune cells and induces robust anti-tumour immunity in preclinical mouse model.
硼中子俘获疗法可在临床前小鼠模型中保护免疫细胞并诱导强大的抗肿瘤免疫力。
Stress-Programmed Immune Niches Fuel TNFR2+ Treg Activation and Drive Neoadjuvant Chemotherapy Resistance in Breast Cancer.
应激编程的免疫微环境促进 TNFR2+ Treg 激活,并驱动乳腺癌新辅助化疗耐药性。
Combined Photothermal and mTOR-Targeted Therapy Overcomes Immune Evasion and Enhances Checkpoint Blockade Efficacy in Metastatic Triple-Negative Breast Cancer.
光热疗法与 mTOR 靶向疗法相结合可克服免疫逃逸并增强转移性三阴性乳腺癌的检查点阻断疗效。
Anti-cancer immune priming with β-radioligand therapy using a novel high affinity antibody selectively targeting the 4Ig-Isoform of B7-H3.
利用新型高亲和力抗体选择性靶向 B7-H3 的 4Ig 同工型,通过 β-放射性配体疗法进行抗癌免疫启动。
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