Anti-CD8 alpha antibody [EPR21769] (Ab217344)

CD8a, Lyt-2, Lyt2, Cd8a, T-cell surface glycoprotein CD8 alpha chain, T-cell surface glycoprotein Lyt-2

反应种属:Mouse
抗原名称:CD8A
应用:WB, IHC, FCM, IP

用户验证的应用

推荐稀释比例

  • IHC-P1/2000 Background staining was observed in mouse testis samples. Perform heat-mediated antigen retrieval with Tris/EDTA buffer pH 9.0 before commencing with IHC staining protocol.
  • WB1/1000
  • Flow Cyt1/500
  • IP1/30
  • IHC-Fr1/500

详细信息

免疫原The exact immunogen used to generate this antibody is proprietary information.
宿主/亚型Rabbit / IgG
抗体类型Monoclonal
全称Anti-CD8 alpha antibody [EPR21769]
产品形式Liquid
储存缓冲液pH: 7.2 - 7.4 Preservative: 0.01% Sodium azide Constituents: PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA
储存条件运输条件: Conditional Ambient 推荐的短期储存时间: 1-2 weeks 推荐的短期储存条件: +4°C 推荐的长期储存条件: -20°C 储存信息: Avoid freeze / thaw cycle
纯化方式Affinity purification Protein A

背景信息

Anti-CD8 alpha antibody [EPR21769] (ab217344) was developed by Abcam using patented rabbit monoclonal antibody technology and is validated for use in Flow Cyt, IHC-Fr IHC-P, IP and WB. Anti-CD8 alpha antibody [EPR21769] (ab217344) was first used in a scientific publication in 2019 and has been cited over 164 times in peer reviewed journals. It's performance in IHC and Immunofluorescence in mouse samples is trusted by the scientific community. Abcam's high quality manufacturing and validation processes ensure Anti-CD8 alpha antibody [EPR21769] (ab217344) has high sensitivity and specificity alongside high lot-to-lot consistency and reproducibility. Anti-CD8 alpha antibody [EPR21769] (ab217344) has 4 independent reviews from customers. Anti-CD8 alpha antibody [EPR21769] (ab217344) specifically detects CD8 alpha (UniProt ID: P01731; Molecular weight: 25kDa) and is sold in 100 µL and 1 mL selling sizes. Conjugation-ready, carrier free format available for antibody clone EPR21769 - ab230156. Antibody clone EPR21769 is also available pre-conjugated to a variety of labels for your convenience - Alexa Fluor ® 488, Alexa Fluor ® 647, FITC, APC, Alexa Fluor ® 594, Alexa Fluor ® 555, PE ( ab237364, ab237365, ab237367, ab237368, ab277939, ab280863, ab306536 ). CD8 alpha is involved in diseases by aiding cytotoxic T cells in targeting and eliminating infected or malignant cells. CD8 T cell dysfunction is associated with several diseases including Autoimmune disease, cancer and infectious diseases. Patented technology Our RabMAb ® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb ® patents. What are the advantages of a recombinant monoclonal antibody? This product is a recombinant monoclonal antibody, which offers several advantages including - High batch-to-batch consistency and reproducibility - Improved sensitivity and specificity - Long-term security of supply - Animal-free batch production For more information, read more on recombinant antibodies.

文献引用 (496)

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PARP 和 KRAS(G12D) 抑制剂的联合应用,利用 PDAC 的弱点,增强了治疗效果。

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长效白细胞介素-7可提高溶瘤病毒疗法治疗胶质母细胞瘤的疗效。

Li Yuping Derek, Giles David A, Huang Yi, Kesarwani Ashwani, Hu Tong, Page Logan, de Andrade Costa Amanda, Luo Jingqin, Wolfarth Alexandra, Choi Donghoon, Dang Mai T, Kim Albert H, DiPersio John F, Curiel David T, Diamond Michael S, Chheda Milan G

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硼中子俘获疗法可在临床前小鼠模型中保护免疫细胞并诱导强大的抗肿瘤免疫力。

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Stress-Programmed Immune Niches Fuel TNFR2+ Treg Activation and Drive Neoadjuvant Chemotherapy Resistance in Breast Cancer.

应激编程的免疫微环境促进 TNFR2+ Treg 激活,并驱动乳腺癌新辅助化疗耐药性。

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Combined Photothermal and mTOR-Targeted Therapy Overcomes Immune Evasion and Enhances Checkpoint Blockade Efficacy in Metastatic Triple-Negative Breast Cancer.

光热疗法与 mTOR 靶向疗法相结合可克服免疫逃逸并增强转移性三阴性乳腺癌的检查点阻断疗效。

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Glazer Sarah E, Sutton Margie N, Yang Ping, Pisaneschi Federica, Sebastian Manu, Gammon Seth T, Piwnica-Worms David
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