Anti-CD63 antibody [EPR21151] (Ab217345)

CD63, CD63 antigen, Cd63

反应种属:Mouse
抗原名称:CD63 antigen
应用:WB, IF/ICC

详细信息

免疫原The exact immunogen used to generate this antibody is proprietary information.
宿主/亚型Rabbit / IgG
抗体类型Monoclonal
产品形式Liquid
纯化方式Affinity purification Protein A
储存缓冲液pH: 7.2 - 7.4 Preservative: 0.01% Sodium azide Constituents: PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA
储存条件运输条件: Conditional Ambient 推荐的短期储存时间: 1-2 weeks 推荐的短期储存条件: +4°C 推荐的长期储存条件: -20°C 储存信息: Avoid freeze / thaw cycle
无载体蛋白No

背景信息

Product Specifications Anti-CD63 antibody [EPR21151] (ab217345) was developed by Abcam using patented rabbit monoclonal antibody technology and is validated for use in ICC/IF, WB in mouse samples. Anti-CD63 antibody [EPR21151] (ab217345) specifically detects CD63 (UniProt ID: P41731; Molecular weight: 26kDa) and is sold in 100 µL and 1 mL selling sizes. Quality and Validation Abcam's high quality manufacturing and validation processes ensure Anti-CD63 antibody [EPR21151] (ab217345) has high sensitivity and specificity alongside high lot-to-lot consistency and reproducibility. Anti-CD63 antibody [EPR21151] (ab217345) has been cited over 147 times in peer reviewed journals and is trusted by the scientific community. Anti-CD63 antibody [EPR21151] (ab217345) has 5 independent reviews from customers. Related Products Conjugation-ready, carrier free format available for antibody clone EPR21151 - ab227892. Antibody clone EPR21151 is also available pre-conjugated to a variety of labels for your convenience - Alexa Fluor® 488, Alexa Fluor® 647, APC, PE, Alexa Fluor® 594, Alexa Fluor® 555 ( ab233055, ab233056, ab319310, ab319449, ab319803, ab319944 ). Target Information CD63, also known as LAMP3 or Granulophysin, is a member of the tetraspanin family and is widely expressed on the surface of various cells, including macrophages and lymphocytes. It plays a crucial role in the formation and release of exosomes. CD63 (Granulophysin) is highly expressed in various tumor cells and also impacts the tumor microenvironment (TME) by regulating cell communication. Additionally, CD63 facilitates the degradation of the extracellular matrix, aiding in tumor cell invasion and metastasis. Species reactivity Human, Rat: We have preliminary internal testing data to indicate this antibody may not react with these species. Please contact us for more information. Patented technology Our RabMAb ® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb ® patents. What are the advantages of a recombinant monoclonal antibody? This product is a recombinant monoclonal antibody, which offers several advantages including - High batch-to-batch consistency and reproducibility - Improved sensitivity and specificity - Long-term security of supply - Animal-free batch production For more information, read more on recombinant antibodies.

文献引用 (241)

The Phospholipid Bis(monoacylglycero)Phosphate Confers Antitumour Immunogenicity to Exosomes Secreted by Dendrogenin A, Which Activates Its Biosynthesis in Tumour Cells.

磷脂双(单酰甘油)磷酸赋予树突状细胞素 A 分泌的外泌体抗肿瘤免疫原性,从而激活肿瘤细胞中树突状细胞素 A 的生物合成。

NCOA4-Mediated Ferritinophagy Induces Ferroptosis and Enriches Ferritin-Containing EVs via Ferritin Phase Separation to Promote Mechanical Ventilation-Induced Pulmonary Fibrosis.

NCOA4 介导的铁蛋白自噬诱导铁死亡,并通过铁蛋白相分离富集含铁蛋白的细胞外囊泡,从而促进机械通气诱导的肺纤维化。

Mannose Oligosaccharide-Conjugated In Situ Pore-Forming Injectable Hydrogels for Rheumatoid Arthritis Treatment by Reprogramming Macrophage Extracellular Vesicles

通过重编程巨噬细胞外囊泡,制备用于治疗类风湿性关节炎的甘露糖寡糖偶联原位成孔注射水凝胶

Anan Zhang,Yifan Ma,Yutong Liu,Shiyan Dong,Michelle Najarro Torres,Betty Y S Kim,Changsheng Liu,Lili Sun,Yuan Yuan,Wen Jiang

Aptamer-functionalized exosomes combined with doxorubicin suppress GBM progression and enhance chemoradiosensitivity by promoting pyroptosis.

适体功能化的外泌体与阿霉素联合使用,通过促进细胞焦亡抑制胶质母细胞瘤进展并增强化疗和放射敏感性。

Wang Jing, Peng Li, Zhong Xinxin, Zheng Siqi, Liang Xiuhua, Du Menghan, Xia Xiangning, Guo Ting, Zheng Lidan, Fang Yingying, Tian Yinghong, Shi Yusheng, Zhang Xingmei

MicroRNA-493-5p engineered exosomes delivered via piezoelectric microneedles for epigenetic modulation of macrophages in diabetic wound healing.

利用压电微针递送经 MicroRNA-493-5p 工程改造的外泌体,对糖尿病伤口愈合中的巨噬细胞进行表观遗传调控。

Chen Tao, Ouyang Lizhi, Mi Bobin, Sheng Yishen, Al-Smadi Fawwaz, Xu Hui, Wu Yaosen, Zhang Xiaolei, Zhou Kailiang, Wu Aimin, Wang Xiangyang, Liu Guohui, Zhang Wenqian

Endothelial progenitor cell derived extracellular vesicles promotes wound healing in diabetic mice via activating mobilization and neovascularization.

内皮祖细胞衍生的细胞外囊泡通过激活动员和新生血管形成来促进糖尿病小鼠的伤口愈合。

Bao Yan, Li Zhaoxiang, Du Lingjuan, Li Yuqian, Yang Yong

Airway basal stem cell derived extracellular vesicles promote lung repair in chronic obstructive pulmonary disease.

气道基底干细胞衍生的细胞外囊泡促进慢性阻塞性肺病中的肺修复。

Zou Mengyu, Hua Ying, Zhao Yu, Shah Suleman, Zuo Wei

Biomimetic fractal topography enhances podocyte maturation in vitro.

仿生分形地形可促进体外足细胞成熟。

Liu Chuan, Aggarwal Praful, Wagner Karl T, Landau Shira, Cui Teng, Song Xin, Shamaei Laleh, Rafatian Naimeh, Zhao Yimu, Rodriguez-Ramirez Sonia, Morton Keith, Virlee Elizabeth, Li Chen Yu, Bannerman Dawn, Pascual-Gil Simon, Okhovatian Sargol, Radisic Anastasia, Clotet-Freixas Sergi, Veres Teodor, Sadrzadeh Mohtada, Filleter Tobin, Broeckel Ulrich, Konvalinka Ana, Radisic Milica

Inhalable liposomal delivery of osimertinib and DNA for treating primary and metastasis lung cancer.

吸入式脂质体递送奥希替尼和DNA治疗原发性和转移性肺癌

Fu Xianglei, Shi Yanbin, Wu Hang, Zhang Yankun, Liu Yingying, Wan Xiaoyu, Chen Xiangqin, Zhou Jiamin, Qiu Shengnan, Zhao Xiaogang, Tian Zhongxian, Li Lian, Zang Hengchang, Lin Guimei

Glutamatergic Regulation of miRNA-Containing Intraluminal Vesicle Trafficking and Extracellular Vesicle Secretion From Cortical Neurons

谷氨酸能调控皮层神经元中含miRNA的腔内囊泡运输和细胞外囊泡分泌

Marcela Bertolio ,Qiyi Li ,Francesca E Mowry ,Kathryn E Reynolds ,Rashed Alananzeh ,Haichao Wei ,Kyoeun Keum ,Rachel Jarvis ,Jiaqian Wu ,Yongjie Yang
  • 1
  • 2
  • 3
  • 4
  • 5
  • 6
  • 25