Anti-MMP13 antibody [EPR21778] (Ab219620)

Collagenase 3, Matrix metalloproteinase-13, MMP-13, MMP13

反应种属:Human, Mouse, Rat
抗原名称:MMP13
应用:IHC

用户验证的应用

推荐稀释比例

  • IHC-P1/2000 For human. Use at 1/500 dilution for mouse and rat. Recommend to incubate the primary antibody at 4C overnight and use the HRP-polymer secondary antibody to detect. Perform heat-mediated antigen retrieval with Tris/EDTA buffer pH 9.0 before commencing with IHC staining protocol.

详细信息

免疫原The exact immunogen used to generate this antibody is proprietary information.
宿主/亚型Rabbit / IgG
抗体类型Monoclonal
全称Anti-MMP13 antibody [EPR21778]
产品形式Liquid
储存缓冲液pH: 7.2 - 7.4 Preservative: 0.01% Sodium azide Constituents: PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA
储存条件运输条件: Conditional Ambient 推荐的短期储存时间: 1-2 weeks 推荐的短期储存条件: +4°C 推荐的长期储存条件: -20°C 储存信息: Avoid freeze / thaw cycle
纯化方式Affinity purification Protein A

背景信息

What is this antibody validated in? Anti-MMP13 antibody [EPR21778] (ab219620) is a rabbit recombinant monoclonal antibody and is validated for use in Immunohistochemistry (IHC-P) in Human, Mouse, Rat samples. Trusted by the scientific community Anti-MMP13 [EPR21778] (ab219620) was first used in a scientific publication in 2018 and has been cited over 30 times in peer-reviewed journals. Other related products We have a range of other formats of antibody clone [EPR21778] also available for your convenience: ab219620, Carrier free - ab237604 Patented technology Our RabMAb ® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb ® patents. What are the advantages of a recombinant monoclonal antibody? This product is a recombinant monoclonal antibody, which offers several advantages including - High batch-to-batch consistency and reproducibility - Improved sensitivity and specificity - Long-term security of supply - Animal-free batch production For more information, read more on recombinant antibodies. Trial sizes available! Test your antibody or perform pre-screening before committing to a larger quantity. Sold in 20µl. Discover our selection of trial-size antibodies.

文献引用 (74)

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CILP Inhibits hyaline cartilage fibrosis and chondrocyte ferroptosis via keap1-Nrf2 axis in early osteoarthritis exercise therapy.

CILP 通过 keap1-Nrf2 轴抑制早期骨关节炎运动疗法中的透明软骨纤维化和软骨细胞铁死亡。

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EGR1/miR-4306/MAT2A axis aggravates pyroptosis and extracellular matrix degradation of nucleus pulposus cells in intervertebral disc degeneration.

EGR1/miR-4306/MAT2A 轴加剧椎间盘退变中髓核细胞的焦亡和细胞外基质降解。

The ganglioside GD3 and its synthase (ST8SIA1) as novel senescence markers associated with osteoarthritis.

神经节苷脂 GD3 及其合成酶 (ST8SIA1) 作为与骨关节炎相关的新型衰老标志物。

Fissoun Christina, Maroun Georges, Silva Raissa, Milano Margot, Guibert Benoit, Dagneaux Louis, Ferreira-Lopez Rosanna, Commes Thérèse, Gilson Eric, Jorgensen Christian, Cherfils-Vicini Julien, Pers Yves-Marie, Brondello Jean-Marc

Targeting CCNB1 Repressed Cartilage Degradation Induced by Inflammation Through NF-κB Pathway in Osteoarthritis.

靶向 CCNB1 可抑制骨关节炎中炎症通过 NF-κB 通路诱导的软骨退化。

Li Hua, Qiao Yuxue, Ding Mengshuang, Liu Yirong

Rejuvenating Hyaline Cartilage with Senescence-Targeting Si-ADAM19 Delivery for Osteoarthritis Therapy.

利用靶向衰老的 Si-ADAM19 递送技术使透明软骨恢复活力,用于骨关节炎治疗

Wang Jiasheng, Guo Peng, Wu Dongmei, Yi Junzhi, Jiang Qi, Hu Jiajie, Ouyang Hongwei

Extracellular vesicles from adipose-derived stromal/stem cells reprogram dendritic cells to alleviate rat TMJOA by transferring mitochondria

脂肪来源的基质/干细胞产生的细胞外囊泡通过转移线粒体重编程树突状细胞,从而缓解大鼠颞下颌关节骨关节炎。

Ziyi Mei # ,Hanyue Li # ,Chuling Huang ,Shiyong Ma ,Yuejia Li ,Pingmeng Deng ,Sha Zhou ,Aizhuo Qian ,Bin Yang ,Jie Li

Regulating macrophage phenotypes with IL4I1-mimetic nanoparticles in IDD treatment

利用IL4I1模拟纳米颗粒调节IDD治疗中的巨噬细胞表型

Jiaying Luo,Guoxin Jin,Shaoqian Cui,Huan Wang,Qi Liu

A microsphere loaded with chondrocyte-targeting exosomes continuously deliver miR-148a for osteoarthritis therapy.

载有靶向软骨细胞的外泌体的微球可持续释放 miR-148a 用于骨关节炎治疗

Yang Tao, Ma Haiwei, Li Kechi, Xiang Jie, Qiu Jianxin, Ding Yiming, Wang Chengdi, Lai Hehuan, Hu Xingyu, Liu Shijie, Lou Chao, Hong Zhenhua, Chen Zhenzhong, He Dengwei

JP4-039 protects chondrocytes from ferroptosis to attenuate osteoarthritis progression by promoting Pink1/Parkin-dependent mitophagy.

JP4-039 通过促进 Pink1/Parkin 依赖性线粒体自噬来保护软骨细胞免受铁死亡,从而减轻骨关节炎的进展

Xie Ya, Lv Zhongyang, Li Weitong, Lin JinTao, Sun Wei, Guo Hu, Jin Xiaoyu, Liu Yuan, Jiang Ruiyang, Fei Yuxiang, Wu Rui, Shi Dongquan
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