Aging Biol

Ketogenic Diet Reduces Age-Induced Chronic Neuroinflammation in Mice

生酮饮食可减少小鼠因年龄引起的慢性神经炎症

Ezetimibe Lowers Risk of Alzheimer's and Related Dementias over Sevenfold, Reducing Aggregation in Model Systems by Inhibiting 14-3-3G::Hexokinase Interaction

依折麦布可降低阿尔茨海默病和相关痴呆症的风险七倍以上，通过抑制 14-3-3G::己糖激酶相互作用减少模型系统中的聚集

Early-Onset Hearing Loss in Mouse Models of Alzheimer's Disease and Increased DNA Damage in the Cochlea

阿尔茨海默病小鼠模型中早发性听力损失和耳蜗 DNA 损伤增加

Damage-Induced Senescent Immune Cells Regulate Regeneration of the Zebrafish Retina.

Intermittent Methionine Restriction Reduces Marrow Fat Accumulation and Preserves More Bone Mass than Continuous Methionine Restriction.

间歇性限制蛋氨酸摄入比持续限制蛋氨酸摄入更能减少骨髓脂肪堆积并保持骨量

Mild Uncoupling of Mitochondria Synergistically Enhances Senolytic Specificity and Sensitivity of BH3 Mimetics.

线粒体轻度解偶联可协同增强 BH3 模拟物的衰老细胞清除特异性和敏感性

Cellular senescence exacerbates features of aging in the eyes

细胞衰老加剧了眼睛的衰老特征

Senolytics Reduce Endothelial Cell DNA Damage and Telomere Dysfunction Despite Reductions in Telomere Length.

尽管端粒长度缩短，但衰老细胞清除剂可减少内皮细胞 DNA 损伤和端粒功能障碍

FGF21 has a sex-specific role in calorie-restriction-induced beiging of white adipose tissue in mice

FGF21 在小鼠热量限制诱导的白色脂肪组织褐变中具有性别特异性作用