Serum Tryptophan-Derived Quinolinate and Indole-3-Acetate Are Associated With Carotid Intima-Media Thickness and its Evolution in HIV-Infected Treated Adults.

血清色氨酸衍生的喹啉酸和吲哚-3-乙酸与 HIV 感染治疗成人的颈动脉内膜中层厚度及其演变相关

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作者：Boyd Anders, Boccara Franck, Meynard Jean-Luc, Ichou Farid, Bastard Jean-Philippe, Fellahi Soraya, Samri Assia, Sauce Delphine, Haddour Nabila, Autran Brigitte, Cohen Ariel, Girard Pierre-Marie, Capeau Jacqueline
期刊：Open Forum Infectious Diseases影响因子：3.800
时间：2019起止号：2019 Dec 6; 6(12):ofz516
doi：10.1093/ofid/ofz516研究方向： 其它
BACKGROUND: HIV-infected individuals undergoing effective antiretroviral therapy (ART) present an increased risk of atherosclerotic cardiovascular disease. We identified serum metabolites associated with carotid intima-media thickness (c-IMT) and its evolution. METHODS: One hundred forty-three hydrophilic serum metabolites were measured by ultraperformance liquid chromatography coupled with high-resolution mass spectrometry in 49 HIV+†ART+, 48 HIV+â€

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