Toll-like receptor 2 in serum: a potential diagnostic marker of prosthetic joint infection?

血清中 Toll 样受体 2:假体关节感染的潜在诊断标志物?

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作者:Galliera Emanuela, Drago Lorenzo, Vassena Christian, Romanò Carlo, Gioia Marazzi Monica, Salcito Lucia, Corsi Romanelli Massimiliano M
Prosthetic joint infection (PJI) is a severe complication of arthroplasty and is still lacking diagnostic gold standards. PJI patients display high Toll-like receptor 2 (TLR2) serum levels, correlating with canonical inflammatory markers (C-reactive protein [CRP], interleukin 6 [IL-6], tumor necrosis factor alpha [TNF-α], and IL-1). Therefore, TLR2 serum levels could be considered a new potential diagnostic tool in the early detection of PJI.

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