Prosthetic joint infection (PJI) is a severe complication of arthroplasty and is still lacking diagnostic gold standards. PJI patients display high Toll-like receptor 2 (TLR2) serum levels, correlating with canonical inflammatory markers (C-reactive protein [CRP], interleukin 6 [IL-6], tumor necrosis factor alpha [TNF-α], and IL-1). Therefore, TLR2 serum levels could be considered a new potential diagnostic tool in the early detection of PJI.
Toll-like receptor 2 in serum: a potential diagnostic marker of prosthetic joint infection?
血清中 Toll 样受体 2:假体关节感染的潜在诊断标志物?
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作者:Galliera Emanuela, Drago Lorenzo, Vassena Christian, Romanò Carlo, Gioia Marazzi Monica, Salcito Lucia, Corsi Romanelli Massimiliano M
| 期刊: | Journal of Clinical Microbiology | 影响因子: | 5.400 |
| 时间: | 2014 | 起止号: | 2014 Feb;52(2):620-3 |
| doi: | 10.1128/JCM.02727-13 | 研究方向: | 信号转导 |
| 信号通路: | Toll-Like Receptor | ||
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