Establishment of an induced pluripotent stem cell line (FDEENTi001-A) from a patient with pathological myopia.

从一名病理性近视患者身上建立诱导多能干细胞系(FDEENTi001-A)

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作者:Bai Xinyue, Yang Xianjie, Cheng Yun, Chen Ling
Pathological myopia (PM) is a retinal degenerative disease with an increasing prevalence in Asia. The peripheral blood mononuclear cells (PBMCs) from a patient with PM were successfully reprogrammed to induced pluripotent stem cells (iPSCs) using integration-free method, Sendai viral (SeV) vectors expressing OCT4, SOX2, KLF4 and C-MYC. This line may provide a useful resource for exploring the pathogenesis of PM.

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