Pathological myopia (PM) is a retinal degenerative disease with an increasing prevalence in Asia. The peripheral blood mononuclear cells (PBMCs) from a patient with PM were successfully reprogrammed to induced pluripotent stem cells (iPSCs) using integration-free method, Sendai viral (SeV) vectors expressing OCT4, SOX2, KLF4 and C-MYC. This line may provide a useful resource for exploring the pathogenesis of PM.
Establishment of an induced pluripotent stem cell line (FDEENTi001-A) from a patient with pathological myopia.
从一名病理性近视患者身上建立诱导多能干细胞系(FDEENTi001-A)
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作者:Bai Xinyue, Yang Xianjie, Cheng Yun, Chen Ling
| 期刊: | Stem Cell Research | 影响因子: | 0.700 |
| 时间: | 2019 | 起止号: | 2019 Jan;34:101369 |
| doi: | 10.1016/j.scr.2018.101369 | 研究方向: | 发育与干细胞、细胞生物学 |
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