Six human induced pluripotent stem cell sublines (hiPSCs) were generated from human dermal fibroblasts (HDFs) derived from skin biopsies donated from monozygotic twin women wherein one woman had proven fertility and her sister was infertile due to ovarian failure. Three hiPSC sublines were created from each twin's HDFs. hiPSCs were reprogrammed using Sendai virus vectors and were subsequently positive for markers of self-renewal including OCT4, NANOG, TRA-1-81 and SSEA-4. Pluripotency was further verified using PluriTest. We show here that the hiPSC lines created from the twins are equivalent in measures of pluripotency and self-renewal, despite their differential diagnosis.
Generation of six human induced pluripotent stem cell sublines (MZT01E, MZT01F, MZT01N and MZT02D, MZT02G and MZT02H) for reproductive science research.
生成六种人类诱导多能干细胞亚系（MZT01E、MZT01F、MZT01N、MZT02D、MZT02G 和 MZT02H），用于生殖科学研究
阅读：8
作者：Pandolfi Erica C, Sosa Enrique, Hunt Timothy J, Goldsmith Sierra, Hurlbut Kellie, Silber Sherman J, Clark Amander T
| 期刊： | Stem Cell Research | 影响因子： | 0.700 |
| 时间： | 2021 | 起止号： | 2021 Mar;51:102204 |
| doi： | 10.1016/j.scr.2021.102204 | 种属： | Human |
| 研究方向： | 发育与干细胞、细胞生物学 | ||
特别声明
1、本文转载旨在传播信息，不代表本网站观点，亦不对其内容的真实性承担责任。
2、其他媒体、网站或个人若从本网站转载使用，必须保留本网站注明的“来源”，并自行承担包括版权在内的相关法律责任。
3、如作者不希望本文被转载，或需洽谈转载稿费等事宜，请及时与本网站联系。
4、此外，如需投稿，也可通过邮箱info@biocloudy.com与我们取得联系。