rac-5''-(4-Fluoro-benzyl-idene)-1'-(4-fluoro-phen-yl)-1''-methyl-1',2',3',5',6',7',8',8a'-octa-hydro-dispiro-[acenaphthyl-ene-1,3'-indolizine-2',3''-piperidine]-2,4''(1H)-dione.

In the title E isomer of the racemic compound, C37H32F2N2O2, the pyridinone ring adopts a twisted half-chair conformation with the N atom deviating by -0.355†(3)†à and with the methyl-ene C atom next to octa-hydro-indolizine moiety deviating by 0.415†(3)†à from the mean plane defined by other four atoms. In the octa-hydro-indolizine system, the pyrrolidine ring exhibits an envelope conformation with the fused methyne C atom deviating by 0.6496†(1)†à from the mean plane defined by four other atoms, and the piperidine ring exhibits a distorted chair conformation as evident from the puckering parameters Q = 0.568†(2)†à , θ = 1.0†(2) and Φ = 256†(11)°. In the crystal, C-H⋯O inter-actions connect the mol-ecules into chains along [101].