(1) Background: Oxidative stress plays a pivotal role in the pathogenesis of various diseases, including neurodegenerative disorders, cardiovascular diseases, cancer, and diabetes, highlighting the pressing need for effective antioxidant interventions. (2) Methods: In this study, we aimed to develop and characterise two novel antioxidant formulations, F3 and F4, as therapeutic interventions for oxidative stress-related conditions. (3) Results: The physicochemical characterisation, preformulation analysis, formulation, preparation of filling powders for capsules, capsule content evaluation, and antioxidant activity assessment of the two novel antioxidant formulations were assessed. These formulations comprise a combination of well-established antioxidants like quercetin, biotin, coenzyme Q10, and resveratrol. Through comprehensive testing, the formulations' antioxidant efficacy, stability, and potential synergistic interactions were evaluated. (4) Conclusions: The findings underscore the promising potential of these formulations as therapeutic interventions for oxidative stress-related disorders and highlight the significance of antioxidant interventions in mitigating their progression.
Comprehensive Analysis of Novel Synergistic Antioxidant Formulations: Insights into Pharmacotechnical, Physical, Chemical, and Antioxidant Properties.
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作者:NeacÈu Sorinel Marius, Mititelu Magdalena, Ozon Emma Adriana, Musuc Adina Magdalena, Iuga Izabela Dana Maria, Manolescu Bogdan Nicolae, Petrescu Simona, Pandele Cusu Jeanina, Rusu Adriana, Surdu Vasile-Adrian, Oprea Eliza, Lupuliasa Dumitru, Popescu Ioana Andreea
| 期刊: | Pharmaceuticals | 影响因子: | 4.800 |
| 时间: | 2024 | 起止号: | 2024 May 27; 17(6):690 |
| doi: | 10.3390/ph17060690 | ||
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