Soft elastomeric optical fibers for oxygen change measurements of blood and living tissues: a thermoplastic polyurethane assessment.

用于测量血液和活体组织氧变化的软弹性体光纤:热塑性聚氨酯评估

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作者:Llera Miguel, Laux Edith, Flahaut Frédéric, Jeandupeux Laure, Alvarez Seoane Esteban, Zerbib Maxime, Beugnot Jean-Charles, Potty Philippe
This paper discusses the design, fabrication, and use of thermoplastic polyurethane optical fibers intended for oxygen saturation measurements. It includes an evaluation of the fiber attenuation and the creation of two probes for the measurement assessment. For comparison, a third probe is made using conventional glass optical fibers. The assessment is conducted in two stages: first, absorption measurements are performed using a mixture of methylene blue and intralipid diluted in deionized water; second, a measurement with human blood is conducted to demonstrate the effectiveness of such fibers in measuring blood oxygen saturation. Additionally, a comprehensive study of measurement stability is provided.

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