Temple syndrome diagnosed in an adult patient with clinical autism spectrum disorder

Temple syndrome (TS14) leads to growth failure, precocious puberty, and diabetes mellitus. However, the long-term prognosis, including the development of social behavior in TS14 patients, remains unclarified. We report the clinical course of a male patient with autism spectrum disorder that received a diagnosis of TS14 at 33 years of age. Keywords: Temple syndrome (TS14); autistic spectrum disorders; imprinting disease; natural history.