A common progenitor for retinal astrocytes and oligodendrocytes

视网膜星形胶质细胞和少突胶质细胞的共同祖细胞

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作者:Santiago B Rompani, Constance L Cepko

Abstract

Developing neural tissue undergoes a period of neurogenesis followed by a period of gliogenesis. The lineage relationships among glial cell types have not been defined for most areas of the nervous system. Here we use retroviruses to label clones of glial cells in the chick retina. We found that almost every clone had both astrocytes and oligodendrocytes. In addition, we discovered a novel glial cell type, with features intermediate between those of astrocytes and oligodendrocytes, which we have named the diacyte. Diacytes also share a progenitor cell with both astrocytes and oligodendrocytes.

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