Abstract
OBJECTIVE: To conduct a bibliometric analysis of heart failure (HF) omics research from 2008 to 2024 using CiteSpace, exploring research hotspots and the latest advancements in this field. METHODS: Literature on HF omics research published between January 2008 and December 2024 was retrieved from the web of science core collection. Microsoft Excel 2019 was used to calculate publication volume and growth trends, while CiteSpace 6.2.R4 was employed to generate visual maps and conduct visual analyses of authors, institutions, countries, journals, references, and keywords. RESULTS: A total of 282 articles were included for bibliometric analysis. The results indicate a gradual increase in the number of publications on HF omics research over the past 16 years. The leading research countries in this field are the United States, China, the United Kingdom, Germany, and Italy. Authoritative research institutions include the German Center for Cardiovascular Research, Harvard University, and Brigham and Women's Hospital. The representative researcher is Zannad, Faiez. Key research keywords include biomarkers, coronary heart disease (CHD), pathways, receptors, acute myocardial infarction (AMI), and atrial fibrillation (AF). CONCLUSION: Omics Research in the Field of HF has been steadily increasing year by year. In terms of research directions, hotspots often involve studies related to CHD, AMI, AF, and other associated conditions. Regarding research objectives, the primary focuses include identifying biomarkers, achieving precision medicine, and elucidating gene expression mechanisms.