Response to: Matters Arising in relation to "Evaluating agreement between individual nutrition randomised controlled trials and cohort studies - a meta-epidemiological study"

We respond to the Matters Arising article by Calkins et al. commenting on our meta-epidemiological study "Evaluating agreement between individual nutrition randomised controlled trials and cohort studies". We appreciate the opportunity to respond to the points raised and to clarify the methods and interpretation of our work.