Convergent evolution increases boron transport through SNPs and tandem duplications at BOR1 and BOR2 in Arabidopsis thaliana

趋同进化通过拟南芥中BOR1和BOR2基因的单核苷酸多态性(SNP)和串联重复增强硼的运输

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Abstract

Boron (B) is a crucial micronutrient, particularly in volcanic soils where its deficiency hampers agriculture. Here, we investigate the genetic basis of leaf B accumulation in natural populations of Arabidopsis thaliana that colonized volcanic islands in Cape Verde. Using a combination of genome-wide association studies (GWAS) and mapping in a recombinant intercross population, we identified a case of convergent phenotypic evolution in which multiple variants in the two principal B transporter genes, BOR1 and BOR2, increase leaf B accumulation in parallel. These include multiple tandem duplications at BOR1 that arose independently in different populations. Overall, this study reveals a remarkable case of convergent evolution occurring within a relatively short time scale, where different types of de novo mutations at B efflux transporter genes achieve similar phenotypic outcomes. Further, our findings show that integrating recombinant populations with GWAS in natural populations can improve power to overcome allelic heterogeneity.

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