Integrative analysis of transcriptome and metabolism reveals functional roles of redox homeostasis in low light and salt combined stress in Leymus chinensis

转录组和代谢的整合分析揭示了氧化还原稳态在羊草(Leymus chinensis)低光和盐胁迫复合胁迫中的功能作用

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Abstract

Salt stress is one of the major limiting factors of Leymus chinensis (named sheepgrass) growth, which accelerates inhibitive effects that are particularly concomitant with low light regimes (LL-Salt). However, little is known about physiological and molecular mechanisms under such LL-Salt in sheepgrass. This study aims to uncover the key reprogrammed metabolic pathways induced by LL-Salt through an integrated analysis of transcriptome and metabolism. Results suggested that the growth of sheepgrass seedlings was dramatically inhibited with a ranging of 8 to 20% reduction in F(v)/F(m) in LL-Salt combined treatments. Catalase activities were increased by 40% in LL but significantly decreased in salt stress, ranging from 15 to 46%. Both transcriptome and metabolism analysis reveal that carbon metabolism pathways were significantly enriched in the differentially expressed genes with downregulation by both LL and salt stress treatment. Metabolites involved in the photorespiration pathway, including serine and glycolate, were downregulated in LL while upregulated in salt stress treatment, with the same pattern of expression levels of a photorespiration regulatory gene, glycolate oxidase. Collectively, we found that serval antioxidant redox pathways, including photorespiration, GSG/GSSH redox, and ABA signaling, participated in response to LL and salt combined events and highlighted the roles of cellular redox homeostasis in LL-Salt response in sheepgrass.

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