Abstract
OBJECTIVES: To investigate the knowledge, attitude and practice (KAP) of patients with ischaemia with non-obstructive coronary arteries (INOCA) toward their condition. DESIGN: A cross-sectional study using questionnaires to assess KAP scores among patients with INOCA. PARTICIPANTS: Patients with INOCA from the Xinjiang region of China were enrolled between September 2023 and February 2024. INTERVENTIONS: Data were collected via structured questionnaires covering demographic information and KAP metrics. PRIMARY AND SECONDARY OUTCOME MEASURES: Mean KAP scores were analysed. Correlation analyses and path analysis examined relationships among KAP components, influencing factors and indirect effects. RESULTS: A total of 498 questionnaires were analysed (mean age of participants 54.13±10.91, 59.04% women). The mean KAP scores were 4.41±1.78 (possible range: 0-7 points), 21.29±3.40 (possible range: 6-30 points) and 26.91±6.37 (possible range: 8-40 points), respectively. Spearman correlation analysis found significant correlations between knowledge and attitude (r=0.4954, p<0.001), knowledge and practice (r=0.4589, p<0.001) and attitude and practice (r=0.5959, p<0.001). Path analysis indicated that attitude, income and drinking had direct effects on practice. Knowledge influenced practice both directly and indirectly. Indirect effects on practice were also noted for family history of INOCA, residence, marital status, coronary vascular examination and smoking. CONCLUSIONS: This study reveals suboptimal KAP levels among patients with INOCA in Xinjiang, China, highlighting an urgent need for improved patient education and disease management strategies to enhance understanding and coping with INOCA.