Discussion
Black men and women express higher percentages of α4β7 expressing CD4+ T cells, which may play a role in HIV disease.
Methods
Flow cytometry was used to examine expression of α4β7 and other markers associated with different functional CD4+ T cell subsets in both men and women who inject drugs.
Results
Higher levels of α4β7, CCR5, and CCR6 were observed on CD4+ T cells from black participants compared with white participants. In a multivariable model, α4β7 expression differed by race, but not sex, age, or other factors.