Modeling heterogeneity of Sudanese hospital stay in neonatal and maternal unit: non-parametric random effect models with Gamma distribution

利用伽马分布的非参数随机效应模型对苏丹新生儿和产科病房住院时间的异质性进行建模

阅读:2

Abstract

OBJECTIVE: Studies looking into patient and institutional variables linked to extended hospital stays have arisen as a result of the increased focus on severe maternal morbidity and mortality. Understanding the length of hospitalization of patients after delivery is important to gain insights into when hospitals will reach capacity and to predict corresponding staffing or equipment requirements. In Sudan, the distribution of the length of stay during delivery hospitalizations is heavily skewed, with the average length of stay of 2 to 3 days. This study aimed to investigate the use of non-parametric random effect model with Gamma distributed response for analyzing skewed hospital length of stay data in Sudan in neonatal and maternal unit. METHODS: We applied Gamma regression models with unknown random effects, estimated using the non-parametric maximum likelihood (NPML) technique [5]. The NPML reduces the heterogeneity in the distribution of the response and produce a robust estimation since it does not require any assumptions on the distribution. The same applies to the log-Gamma link that does not require any transformation for the data distribution and it can handle the outliers in the data points. In this study, the models are fitted with and without covariates and compared using AIC and BIC values. RESULTS: The findings imply that in the context of health care database investigations, Gamma regression models with non-parametric random effect consistently reduce heterogeneity and improve model accuracy. The generalized linear model with covariates and random effect (k = 4) had the best fit, indicating that Sudanese hospital length of stay data could be classified into four groups with varying average stays influenced by maternal, neonatal, and obstetrics data. CONCLUSION: Identifying factors contributing to longer stays allows hospitals to implement strategies for improvement. Non-parametric random effect model with Gamma distributed response effectively accounts for unobserved heterogeneity and individual-level variability, leading to more accurate inferences and improved patient care. Including random effects can significantly affect variable significance in statistical models, emphasizing the need to consider unobserved heterogeneity when analyzing data containing potential individual-level variability. The findings emphasise the importance of making robust methodological choices in healthcare research in order to inform accurate policy decisions.

特别声明

1、本页面内容包含部分的内容是基于公开信息的合理引用;引用内容仅为补充信息,不代表本站立场。

2、若认为本页面引用内容涉及侵权,请及时与本站联系,我们将第一时间处理。

3、其他媒体/个人如需使用本页面原创内容,需注明“来源:[生知库]”并获得授权;使用引用内容的,需自行联系原作者获得许可。

4、投稿及合作请联系:info@biocloudy.com。