Epidural anaesthesia restores pancreatic microcirculation and decreases the severity of acute pancreatitis

硬膜外麻醉可恢复胰腺微循环,并减轻急性胰腺炎的严重程度。

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Abstract

AIM: To investigate the effect of epidural anaesthesia (EA) on pancreatic microcirculation during acute pancreatitis (AP). METHODS: AP was induced by injection of sodium taurocholate into the pancreatic duct of Sprague-Dawley rats. To realize EA, a catheter was introduced into the epidural space between T7 and T9 and bupivacaine was injected. Microcirculatory flow was measured by laser Doppler flowmetry. Arterial blood gas analyses were performed. At the end of the experiment (

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