Increased hepatocyte growth factor levels over 2 years are associated with coronary heart disease: the Multi-Ethnic Study of Atherosclerosis (MESA)

两年内肝细胞生长因子水平升高与冠心病有关:动脉粥样硬化多民族研究 (MESA)

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作者:Paul A Decker, Nicholas B Larson, Elizabeth J Bell, James S Pankow, Naomi Q Hanson, Christina L Wassel, Michael Y Tsai, Suzette J Bielinski

Abstract

Hepatocyte growth factor (HGF) is associated with subclinical and clinical atherosclerosis. However, the significance of change in HGF and development of atherosclerotic disease is unknown. In a large and diverse population-based cohort, we report that change in the biomarker HGF is an independent predictor of incident CHD.

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