Abstract
The emerging paradigm of "fusion of lifeforms" represents a transformative shift from conventional human-machine interfaces toward deeply integrated symbiotic systems, where biological and artificial components co-adapt structurally, energetically, informationally, and cognitively. This review systematically classifies multi-level perception systems within fusion of lifeforms into four functional categories: sensory and functional restoration, beyond-natural sensing, endogenous state sensing, and cognitive enhancement. We survey recent advances in neuroprosthetics, sensory augmentation, closed-loop physiological monitoring, and brain-computer interfaces, highlighting the transition from substitution to fusion. Despite significant progress, critical challenges remain, including multi-source heterogeneous integration, bandwidth and latency limitations, power and thermal constraints, biocompatibility, and system-level safety. We propose future directions such as layered in-body communication networks, sustainable energy strategies, advanced biointerfaces, and robust safety frameworks. Ethical considerations regarding self-identity, neural privacy, and legal responsibility are also discussed. This work aims to provide a comprehensive reference and roadmap for the development of next-generation fusion of lifeforms, ultimately steering human-machine integration from episodic functional repair toward sustained, multi-level symbiosis between biological and artificial systems.