Bacterial genomic epidemiology, from local outbreak characterization to species-history reconstruction

细菌基因组流行病学:从局部疫情特征分析到物种历史重建

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Abstract

Bacteriology has embraced the next-generation sequencing revolution, swiftly moving from the time of single genome sequencing to the age of genomic epidemiology. Hundreds and now even thousands of genomes are being sequenced for single bacterial species, allowing unprecedented levels of resolution and insight in the evolution and epidemic diffusion of the main bacterial pathogens. Here, we present a review of some of the most recent and groundbreaking studies in this field.

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