Activities of amphotericin B and antifungal azoles alone and in combination against Pseudallescheria boydii

两性霉素B和抗真菌唑类药物单独及联合用药对博伊德假阿利什菌的活性

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Abstract

In order to develop new approaches to treatment of infections due to Pseudallescheria boydii, the in vitro antifungal activity of amphotericin B alone and in combination with miconazole, itraconazole, and fluconazole was studied. Combinations of amphotericin B and antifungal azoles were synergistic, additive, or indifferent in their interaction against P. boydii. Antagonism was not observed.

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